Xanthohumol

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Xanthohumol
Chemical structure of xanthohumol
Names
IUPAC name
(E)-1-[2,4-Dihydroxy-6-methoxy-3-(3-methylbut-2-enyl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one
Identifiers
CAS number6754-58-1 N=
ChEBICHEBI:66331 N
ChEMBLChEMBL253896 YesY
ChemSpider555077 YesY
Jmol-3D imagesImage
PubChem639665
RTECS numberUD5574117
UNIIT4467YT1NT YesY
Properties
C21H22O5
Molar mass354.40 g·mol−1
Density1.24 g/cm3[1]
Melting point157–159 °C (315–318 °F; 430–432 K) [1]
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N verify (what isYesY/N?)
Infobox references
 
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Xanthohumol
Chemical structure of xanthohumol
Names
IUPAC name
(E)-1-[2,4-Dihydroxy-6-methoxy-3-(3-methylbut-2-enyl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one
Identifiers
CAS number6754-58-1 N=
ChEBICHEBI:66331 N
ChEMBLChEMBL253896 YesY
ChemSpider555077 YesY
Jmol-3D imagesImage
PubChem639665
RTECS numberUD5574117
UNIIT4467YT1NT YesY
Properties
C21H22O5
Molar mass354.40 g·mol−1
Density1.24 g/cm3[1]
Melting point157–159 °C (315–318 °F; 430–432 K) [1]
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N verify (what isYesY/N?)
Infobox references

Xanthohumol is a prenylated chalconoid from hops and beer. This prenylated chalconoid is not estrogenic. It has a range of biological properties in animal studies, though only at doses significantly higher than what is available in natural sources,[2] and may have potential therapeutic utility.[3][4]

See also[edit]

References[edit]

  1. ^ a b Xanthohumol from hop (Humulus lupus), Santa Cruz Biotechnology
  2. ^ "Study: Main Ingredient Found In Beer Can Help Improve Memory". CBS Seattle. September 30, 2014. The researchers point out that they gave the mice huge quantities of xanthohumol as dietary supplements and caution people shouldn’t start drinking lots of beer to improve their memories ... A human would have to drink 2000 liters of beer a day to reach the xanthohumol levels we used in this research 
  3. ^ Magalhães, P. J.; Carvalho, D. O.; Cruz, J. M.; Guido, L. F.; Barros, A. A. (2009). "Fundamentals and health benefits of xanthohumol, a natural product derived from hops and beer". Natural product communications 4 (5): 591–610. PMID 19445313. 
  4. ^ Stevens JF, Page JE (May 2004). "Xanthohumol and related prenylflavonoids from hops and beer: to your good health!". Phytochemistry 65 (10): 1317–30. doi:10.1016/j.phytochem.2004.04.025. PMID 15231405.