Xanthohumol is a prenylatedchalconoid from hops and beer. This prenylated chalconoid is not estrogenic. It has a range of biological properties in animal studies, though only at doses significantly higher than what is available in natural sources, and may have potential therapeutic utility.
^"Study: Main Ingredient Found In Beer Can Help Improve Memory". CBS Seattle. September 30, 2014. The researchers point out that they gave the mice huge quantities of xanthohumol as dietary supplements and caution people shouldn’t start drinking lots of beer to improve their memories ... A human would have to drink 2000 liters of beer a day to reach the xanthohumol levels we used in this research
^Magalhães, P. J.; Carvalho, D. O.; Cruz, J. M.; Guido, L. F.; Barros, A. A. (2009). "Fundamentals and health benefits of xanthohumol, a natural product derived from hops and beer". Natural product communications4 (5): 591–610. PMID19445313.