Westhoff is an unincorporated community in northwestern DeWitt County, Texas, United States. The town began as a depot on the Galveston, Harrisburg and San Antonio Railway in 1906. Early on the town was named Bello, but that was rejected as it bore too close a similarity to a similarly named town, Bells. The town suffered a serious fire in 1913. The population of the town peaked at near 500 in the mid-1920s, and since the 1960s most official documents list the town population at 410, where it remained as of 2000.
The climate in this area is characterized by hot, humid summers and generally mild to cool winters. According to the Köppen Climate Classification system, Westhoff has a humid subtropical climate, abbreviated "Cfa" on climate maps.