Udenafil

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Udenafil
Udenafil.svg
Systematic (IUPAC) name
3-(1-methyl-7-oxo-3-propyl-4,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-N-[2-(1-methylpyrrolidin-2-yl)ethyl]-4-propoxybenzenesulfonamide
Clinical data
Legal status?
Pharmacokinetic data
Half-life7.3–12.1 hours[1]
Identifiers
CAS number268203-93-6 N
ATC codeNone
PubChemCID 6918523
DrugBankDB06267
ChemSpider5293720 YesY
UNIIL5IB4XLY36 YesY
KEGGD10027 N
Chemical data
FormulaC25H36N6O4S 
Mol. mass516.657 g/mol
 N (what is this?)  (verify)
 
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Udenafil
Udenafil.svg
Systematic (IUPAC) name
3-(1-methyl-7-oxo-3-propyl-4,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-N-[2-(1-methylpyrrolidin-2-yl)ethyl]-4-propoxybenzenesulfonamide
Clinical data
Legal status?
Pharmacokinetic data
Half-life7.3–12.1 hours[1]
Identifiers
CAS number268203-93-6 N
ATC codeNone
PubChemCID 6918523
DrugBankDB06267
ChemSpider5293720 YesY
UNIIL5IB4XLY36 YesY
KEGGD10027 N
Chemical data
FormulaC25H36N6O4S 
Mol. mass516.657 g/mol
 N (what is this?)  (verify)

Udenafil is a drug used in urology to treat erectile dysfunction. It belongs to a class of drugs called PDE5 inhibitor, which many other erectile dysfunction drugs such as sildenafil, tadalafil, and vardenafil also belong to. It was developed by Dong-A Pharmaceutical Co., Ltd. and is marketed under the trade name Zydena.[2] With a T max of 1.0-1.5 h and a T 1/2 of 11-13 h (a relatively rapid onset and a long duration of action), both on-demand and once-daily use of udenafil have been reported.[3] Typical doses are 100 and 200 mg. Udenafil is available in Korea, Russia, and Philippines;[4] in the United States, it is not approved for use U.S. Food and Drug Administration.

References[edit]

  1. ^ Udenafil Information
  2. ^ Zydena (udenafil) product information page. Dong-A Pharmaceutical. Retrieved on April 13, 2009.
  3. ^ Udenafil: efficacy and tolerability in the management of erectile dysfunction.
  4. ^ Zydena, drugs.com