The UT Health Science Center is the largest health sciences university in South Texas. The Health Science Center serves San Antonio and all of the 50,000 square miles (130,000 km2) area of Central and South Texas. It extends to campuses in the Texas border communities of Laredo and the Lower Rio Grande Valley.
The Health Science Center has produced more than 28,000 graduates; more than 3,000 students a year train in an environment that involves more than 100 affiliated hospitals, clinics and health care facilities in South Texas. The university offers more than 65 degrees, the large majority of them being graduate and professional degrees, in the biomedical and health sciences fields.
The Health Science Center is home to the Cancer Therapy & Research Center (CTRC) at The University of Texas Health Science Center San Antonio, designated a National Cancer Institute Cancer Center. The CTRC's Institute for Drug Development (IDD) is internationally recognized for conducting one of the largest oncology Phase I clinical drug trials programs in the world. Fifteen of the cancer drugs most recently approved by the U.S. Food & Drug Administration underwent development or testing at the IDD. Other noted programs include: cellular and structural biology, urology, nephrology, transplantation biology, aging and longevity studies, cardiology and research imaging. The Health Science Center publishes a periodic magazine, The Mission.
In 2006, $263 million of facility upgrades were allocated for the campus by the University of Texas System Board of Regents. This included a $150 million 200,000-square-foot (19,000 m2) South Texas Research Facility (designed by architect Rafael Vinoly). The building was dedicated in October 2011.
The university is one of four medical schools in the University of Texas System. UT Austin's Pharmacy School is also partially located on this campus. The school has eight campuses, spanning 250 acres (1.0 km2) in total:
Joe R. and Teresa Lozano Long Campus
Greehey Academic and Research Campus
Texas Research Park Campus
Medical Arts & Research Center
Cancer Therapy & Research Center at The University of Texas Health Science Center San Antonio
University Hospital ranked among top 50 hospitals in the U.S. in three specialties: Respiratory Disorders, Kidney Disease and Hormonal Disorders (endocrinology, including diabetes care) for the sixth consecutive year (2005).
The Palmaz Stent, developed by Dr. Julio Palmaz, has been named "one of the most important inventions in modern medicine".
Health Science Center faculty members are among the world's most cited scientific authors, listed in the top one-half of one percent of all published scientists.
A Latin copy of Avicenna's Canon of Medicine, dated 1484, located at the P.I. Nixon Medical Historical Library.
1959: South Texas Medical School is chartered.
1966: First class of 15 students is admitted to the Medical School; temporarily housed at Trinity University.
1969: Legislature authorizes creation of Dental School.
1970: Legislature authorizes School of Nursing.
1972: School of Allied Health Sciences and Graduate School of Biomedical Sciences created Institution is officially designated The University of Texas Health Science Center at San Antonio. Frank Harrison, M.D., Ph.D., appointed first president.
1976: Responsibility for the School of Nursing is transferred to the U. T. Health Science Center from the U. T. Nursing School at Austin.
1987: Gift of $15 million from H. Ross Perot finances creation of Institute of Biotechnology.
1998: State Legislature authorizes creation of a Regional Academic Health Center in the Lower Rio Grande Valley (RAHC), to be administered by the Health Science Center’s Medical School.
1999: Health Science Center is designated to receive a $200 million public endowment from the State of Texas to establish a Children’s Cancer Research Institute Construction begins on new South Texas Centers for Biology in Medicine at the Texas Research Park.
2002: The Regional Academic Health Center in the Lower Rio Grande Valley (RAHC) opens its doors for medical students and residents.
Copy of Garencières' 1672 English translation of the Propheties, located in The P.I. Nixon Medical History Library.
2003: Health Science Center receives largest grant to date for a $37 million study of small subcortical strokes, the most common type of stroke in South Texas. Health Science Center and UT San Antonio sign an agreement to establish the San Antonio Life Sciences Institute, a new collaborative research and education partnership. President Cigarroa announces a $300 million initiative to build a Research Tower in the South Texas Medical Center and recruit leading scientists for it.
2004: Health Science Center dedicates $50 million Children's Cancer Research Institute, where scientists currently study formation and development of cancer in children and adults.
2006: The Regional Academic Health Center - Medical Research Division (E-RAHC)  was dedicated April 25, 2006 on the campus of UT Pan American in Edinburg. Also administered by the Health Science Center, this division provides state-of-the-art laboratory space and equipment for scholars and scientists to conduct research on critical health problems of the South Texas/Border Region.
2007: Health Science Center receives a $25 million donation from the Greehey Family Foundation.
2007: Health Science Center receives a $25 million donation from Joe R. and Teresa Lozano Long. The central campus is renamed the Joe R. and Teresa Lozano Long Campus.
2007: The second facility was dedicated at The Regional Academic Health Center in the Lower Rio Grande Valley  campus - the Academic and Clinical Research building. This facility houses the RAHC clinical research center and also the South Texas VA Health Care Center.
2008: University Hospital announces plans for a $1 billion expansion that includes a new trauma tower.
State SenatorLeticia Van de Putte championed the creation of a special advisory group that would research the benefits of a possible merger between the Health Science Center and the University of Texas at San Antonio (UTSA), which is also located on the city's northwest side. In 2010, the special advisory group, headed by Peter Flawn, former president of both UTSA and the University of Texas at Austin, concluded that a merger would not be in the best interest of the two institutitons. Among its key arguments were that both institutions had strong leadership already on a positive trajectory, the merger would be a short-term distraction for UTHSCSA and the benefit to UTSA's national stature would be slight.
The Health Science Center has a public-private partnership that is designed to promote Nobel Laureate-worthy research at the institution. The $300 million project, entitled "The Campaign for the Future of Health", seeks to build new infrastructure with the South Texas Research Facility and the President's Excellence Fund.
Dental School: Community Dentistry, Dental Diagnostic Science, Endodontics, General Dentistry, Oral and Maxillofacial Surgery, Orthodontics, Pediatric Dentistry, Periodontics, Prosthodontics, Restorative Dentistry.