There is preliminary evidence that Triphala contains compounds with antioxidant properties in isolated cells and rats, however this has not yet been demonstrated in people. Triphala has significant immunostimulatory effects on cellular immune response, especially cytotoxicT cells and natural killer cells. Increases in the absolute number of these cells may provide a novel adjuvant therapy for HIV/AIDS positive people in terms of immunological improvement. Triphala extract significantly prevents selenite induced experimental cataractogenesis in vitro and in vivo for rats. Recently, triphala's active ingredient chebunilic acid have been found to have the anti-tumour activity through suppression of vascular endothelial growth factor-A (VEGF) action.
^Jagetia, GC; Baliga, MS; Malagi, KJ; Sethukumar Kamath, M (Mar 2002). "The evaluation of the radioprotective effect of Triphala (an ayurvedic rejuvenating drug) in the mice exposed to gamma-radiation.". Phytomedicine : international journal of phytotherapy and phytopharmacology9 (2): 99–108. PMID11995956.
^ abReddy TC, Aparoy P, Babu NK, Kalangi SK, Reddanna P (May 2010). "Kinetics and Docking Studies of a COX-2 Inhibitor Isolated from Terminalia bellerica Fruits". Protein Pept Lett17 (10): 1251–7. PMID20441561.
^Pawar V, Lahorkar P, Anantha Narayana DB. Development of a RP-HPLC method for analysis of Triphala curna and its applicability to test variations in Triphala curna preparations. Indian J Pharm Sci [serial online] 2009 [cited 2010 Aug 1];71:382-6. Available from: http://www.ijpsonline.com/text.asp?2009/71/4/382/57286
^Mahesh R, Bhuvana S, Begum VM (August 2009). "Effect of Terminalia chebula aqueous extract on oxidative stress and antioxidant status in the liver and kidney of young and aged rats". Cell Biochem. Funct.27 (6): 358–63. doi:10.1002/cbf.1581. PMID19548245.
^Srikumar R, Parthasarathy NJ, Manikandan S, Narayanan GS, Sheeladevi R (February 2006). "Effect of Triphala on oxidative stress and on cell-mediated immune response against noise stress in rats". Mol. Cell. Biochem.283 (1-2): 67–74. doi:10.1007/s11010-006-2271-0. PMID16444587.
^Phetkate, Pratya; Kummalue, Tanawan; U-pratya, Yaowalak; Kietinun, Somboon. "Significant Increase in Cytotoxic T Lymphocytes and Natural Killer Cells by Triphala: A Clinical Phase I Study". Evidence-Based Complementary and Alternative Medicine2012: 1–6. doi:10.1155/2012/239856.
^Gupta, SureshKumar; Kalaiselvan, V; Srivastava, Sushma; Agrawal, ShyamS; Saxena, Rohit. "Evaluation of anticataract potential of Triphala in selenite-induced cataract: In vitro and in vivo studies". Journal of Ayurveda and Integrative Medicine1 (4): 280. doi:10.4103/0975-9476.74425.
^Lu, Kai; Chakraborty, Debanjan; Sarkar, Chandrani; Lu, Tingting; Xie, Zhiliang; Liu, Zongfa; Basu, Sujit (24 August 2012). "Triphala and Its Active Constituent Chebulinic Acid Are Natural Inhibitors of Vascular Endothelial Growth Factor-A Mediated Angiogenesis". PLOS one7 (8): 7. doi:10.1371/journal.pone.0043934.