Trephine

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A trephine with a center pin can be seen on the left.
Dr. John Clarke trepanning a skull, ca. 1664, in one of the earliest American portraits. Clarke has a trephine in his right hand. The painting is in Harvard Medical School.[1]

A trephine (/trɨˈfn/; from Latin trypan, meaning to bore)[2][dubious ] is a surgical instrument with a cylindrical blade. It can be of one of several dimensions and designs depending on what it is going to be used for. They may be specially designed for obtaining a cylindrically shaped core of bone that can be used for tests and bone studies, cutting holes in bones (i.e., the skull) or for cutting out a round piece of the cornea for eye surgery.

A cylindrically shaped core of bone (or bone biopsy) obtained with a bone marrow trephine is usually examined in the histopathology department of a hospital under a microscope. It shows the pattern and cellularity of the bone marrow as it lay in the bone and is a useful diagnostic tool in certain circumstances such as bone marrow cancer and leukemia.[citation needed]

See also[edit]

References[edit]

  1. ^ Holmes, Oliver Wendell (September 18, 2008). Medical Essays. (Webster's French Thesaurus Edition). Icon Group International. Google Books. Retrieved April 2, 2014.
  2. ^ Mosby's Medical, Nursing & Allied Health Dictionary, Fourth Edition, Mosby-Year Book Inc., 1994, p. 1584