As a freshman at Garfield High School, Wroten averaged 20.8 points, 8.7 rebounds and 3.8 assists per game. He was named to the 2009 All-Washington State Class 4A first team, becoming the first ever freshman to be named to the first team. In his sophomore season, Wroten averaged 17.6 points, 6.4 rebounds and 4.9 assists per game. Wroten was forced to sit out his junior season after an ACL injury in a football game. During his senior season, Wroten averaged 25.0 points, 7.5 rebounds and 4.1 assists per game.
In his freshman season at Washington, Wroten averaged 16.7 points, 5.0 rebounds and 3.6 assists per game. This was good enough for him to be named Pac-12 Freshman of the Year and to be named to the All-Pac-12 first team. He was the first ever freshman from Washington to be named to the All-Pac-12 Team. On April 3, 2012 Wroten decided to enter his name in the 2012 NBA Draft. Wroten's Washington teammate Terrence Ross also decided to enter his name in the 2012 NBA Draft.
Wroten was drafted by the Memphis Grizzlies in the first round with the 25th overall pick in the 2012 NBA Draft. During his rookie season, he had several assignments with the Reno Bighorns of the NBA D-League. On August 22, 2013, the Grizzlies traded Wroten to the Philadelphia 76ers in exchange for a future 2nd round pick and a trade exception. On November 8, 2013, he scored 18 points along with 4 rebounds, and 4 assists in a 94 to 79 win over the Cleveland Cavaliers. On November 13, 2013 in his first career start he recorded his first triple double with 18 points, 10 rebounds, and 11 assists in an 123 to 117 overtime win against the Houston Rockets. This was the first time in NBA history that a player put up a triple double in their first career start. On November 15, 2013 he scored 22 points along with 6 assists in a 113 to 103 point loss to the Atlanta Hawks. On December 6, 2013 Wroten scored 21 points along with 9 assists and 8 rebounds in a 88 to 105 loss to the Charlotte Bobcats.