Tioconazole

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Tioconazole
Systematic (IUPAC) name
(RS)-1-[2-[(2-Chloro-3-thienyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
Clinical data
Trade namesVagistat-1
AHFS/Drugs.commonograph
Pregnancy cat. ?
Legal status ?
RoutesTopical
Identifiers
CAS number65899-73-2 YesY
ATC codeD01AC07 G01AF08
PubChemCID 5482
DrugBankDB01007
ChemSpider5282 N
UNIIS57Y5X1117 N
KEGGD00890 YesY
ChEMBLCHEMBL1200438 N
SynonymsThioconazole
Chemical data
FormulaC16H13Cl3N2OS 
Mol. mass387.711 g/mol
 N (what is this?)  (verify)
 
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Tioconazole
Systematic (IUPAC) name
(RS)-1-[2-[(2-Chloro-3-thienyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
Clinical data
Trade namesVagistat-1
AHFS/Drugs.commonograph
Pregnancy cat. ?
Legal status ?
RoutesTopical
Identifiers
CAS number65899-73-2 YesY
ATC codeD01AC07 G01AF08
PubChemCID 5482
DrugBankDB01007
ChemSpider5282 N
UNIIS57Y5X1117 N
KEGGD00890 YesY
ChEMBLCHEMBL1200438 N
SynonymsThioconazole
Chemical data
FormulaC16H13Cl3N2OS 
Mol. mass387.711 g/mol
 N (what is this?)  (verify)

Tioconazole is an antifungal medication of the imidazole class used to treat infections caused by a fungus or yeast. It is marketed under the brand names Trosyd and Gyno-Trosyd (Pfizer). Tioconazole ointments serve to treat women's vaginal yeast infections.[1] They are available in one day doses, as opposed to the 7-day treatments more common in use in the past.

Tioconazole topical (skin) preparations are also available for ringworm, jock itch, athlete's foot, and tinea versicolor or "sun fungus".

Side effects[edit source | edit]

Side effects (for the women's formulas) may include temporary burning/irritation of the vaginal area, moderate drowsiness, headache similar to a sinus headache, hives, and upper respiratory infection.[citation needed] These side effects may be only temporary, and do not normally interfere with the patient's comfort enough to outweigh the end result.

References[edit source | edit]

  1. ^ Tioconazole, Mayo Clinic