Bugs Bunny (voiced by Jeff Bergman) – Bugs Bunny lives a life of upper-middle-class suburban leisure, based off income from a popular Carrot Peeler that he invented. He lives in a well-appointed house, drives a compact car, and provides room and board for his friend, Daffy Duck. He spends his time watching sports on TV, hanging out with his friends and neighbors (mostly drawn from the classic Looney Tunes roster), and dating Lola Bunny (the latter under some protest). He generally plays the straight man to Daffy and Lola's various bouts of insanity, although he is not without his own quirks. He has exhibited somewhat compulsive/addictive tendencies, like having a high caffeine intake with coffee, becoming addicted to an energy drink that had dangerous chemicals in it, nearly leveled his own house in an increasingly deranged attempt to put up a shelf, and getting hooked on foods that contain butter. Despite being very intelligent, he has shown some level of idiocy, such as when he found jail "a smart aleck's" paradise and mistook the Tasmanian Devil for a dog.
Daffy Duck (voiced by Jeff Bergman) – Daffy Duck is the roommate of Bugs Bunny. Unlike Bugs and their neighbors, Daffy has no way of earning money and relies on Bugs for food and shelter. He has tried on numerous occasions to get rich quick, but ended up failing repeatedly. While Daffy's greed and jealousy of Bugs remains, it appears less antagonistic in the show. In the first episode, Bugs openly admits that Daffy is his best friend, despite his faults. Daffy has worked, and been fired from, numerous jobs due to negligence and/or incompetence. Despite this, however, Daffy has shown to be a very skilled hair dresser and successfully graduated beauty school. Daffy's two possessions that he is proud of are this blue recliner and his Papier-mâchéparade float, constructed on top of a pickup truck, which is his main means of transport. In the episode "The Float", it was destroyed by a car wash incident and Daffy sought to replace it with a yacht by tricking Porky into giving him an expensive loan for a kidney transplant. But his less-than-stellar boating skills and a fight with Porky ended that ambition. He is rushed to the hospital and revealed that he actually needed a kidney transplant. Bugs pays the money, and Porky donates a kidney to Daffy. His parade float is repaired shortly after by Porky.
Porky Pig (voiced by Bob Bergen) – Porky Pig is one of Bugs Bunny and Daffy Duck's friends. Despite being extremely bright and bookish, Porky has an innocent, naive quality that Daffy frequently uses to his advantage, tricking Porky into parting with large sums of money or accompanying him in bizarre schemes. Porky originally worked a boring office job, but got fired following Bugs' example. He started his own catering company afterwards. In "Dear John," Porky was shown to have served on the city council. He starts a relationship with Petunia in the end of "Here Comes The Pig". In "Best Friends Redux", Daffy meets Porky's young self and ensures that he becomes good friends with Bugs & Rodney in their cabin, finally showing Porky an act of kindness.
Speedy Gonzales (voiced by Fred Armisen) – Speedy Gonzales is an extremely fast mouse who lives with Bugs and Daffy as their "mouse in the wall" and runs a pizza parlor called Pizzarriba. He is occasionally shown to act as Daffy's conscience. The episode "Sunday Night Slice" showed that Bugs bought his favorite restaurant Girardi's to prevent it from being closed and hired Speedy to help him. When Bugs decides he doesn't want to own a restaurant anymore, he hands ownership of it to Speedy who renames it "Pizzarriba".
Yosemite Sam (voiced by Maurice LaMarche) – Yosemite Sam is one of Bugs and Daffy's neighbors. He is a liar, a thief, and a cheat, amongst other things. He tends to annoy Bugs and Daffy.
Lola Bunny (voiced by Kristen Wiig) – Lola is Bugs' scatter-brained, bubbly, obsessive girlfriend, who has a habit of speaking rapidly, whether anyone else is listening or not. When they first meet, Bugs falls in love with her, but after learning how crazy and ditsy she is, he loses interest and often tries to escape her company. Lola develops a huge obsession with Bugs Bunny that the latter finds creepy; Lola is never put off by Bugs' responses to behaviour, that include taking photos of him in the shower, spying on him late at night, and often stalking him. Later in the series, however, Bugs eventually falls in love with Lola again which started when they went to Paris in the episode "Eligble Bachelors" and Bugs manages to stop her talking for a while.
Tina Russo (voiced by Jennifer Esposito in Season One, Annie Mumolo in Season Two) – A new character original to the show, Tina Russo is a female duck who is Daffy's girlfriend. She works at a copy store called "Copy Place". Tina is another straight character of the show, with a no-nonsense personality. She first starts dating Daffy because "she likes a project"; she tolerates his selfish and arrogant behaviour as she has a keen astuteness which allows her to read between the lines when they first meet; she works out that Daffy he is actually insecure and jealous, and that his vain attitude is really a front. Daffy is amazed she works this out so quickly, and later reveals Tina, through email, that he can't believe someone "so kind, beautiful, generous, and intelligent" would ever want to be with someone like him. After reading this, Tina is touched, and tells Daffy she loves him.
Tasmanian Devil (voiced by Jim Cummings) – In this show, the Tasmanian Devil is portrayed as walking on four legs like a real Tasmanian Devil and his eyes are bloodshot red (later turned yellow when Bugs uses a taming trick that Speedy Gonzales taught him). Initially, Bugs believed Taz to be a dog and kept him as a house pet much to Daffy's discomfort. Eventually, Bugs learned the truth and tried to return him to his home in Tasmania only to find out that Taz would rather live with him. When Taz is not causing trouble for Daffy, he has occasionally tried to eat Sylvester. In the episode 'Ridiculous Journey' Taz spoke for the first time in the series, and had bonded with Sylvester and Tweety.
Pete Puma (voiced by John Kassir) – A dimwitted puma who is one of Daffy Duck's friends and does various jobs around town.
Witch Lezah (voiced by Roz Ryan) – A witch who lives next door to Bugs Bunny and is often annoyed at the antics of Daffy Duck. Witch Lezah is also a hypnotherapist by trade. The character is based on Witch Hazel with 'Lezah' being 'Hazel' spelled backwards.
Granny (voiced by June Foray) – An old lady who is one of Bugs Bunny's neighbors. Granny is revealed to have fought in WWII. In "The Grand Old Duck of York," it is revealed that Granny teaches piano lessons.
Two albums compiling songs from the show have been released digitally by WaterTower Music:
Songs from The Looney Tunes Show, Season One (2012)
Songs from The Looney Tunes Show, Season Two (2013)
This section requires expansion. (January 2012)
Response to The Looney Tunes Show has been mixed. Though the voice acting have received praised. The series has been criticized for its infrequent use of slapstick, its lack of cartoon gags, character designs, and the "sitcom-styled" format that consists of the characters living in a suburban neighborhood.  The show, however, remains consistently popular, garnering an average of 2 million viewers every episode.