Sphincter of ampulla

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sphincter of ampulla
Gray1057.png
Interior of the descending portion of the duodenum, showing bile papilla.
Latinm. sphincter ampullae
MeSHOddi's+Sphincter
CodeTA A05.8.02.018
 
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sphincter of ampulla
Gray1057.png
Interior of the descending portion of the duodenum, showing bile papilla.
Latinm. sphincter ampullae
MeSHOddi's+Sphincter
CodeTA A05.8.02.018

The sphincter of ampulla or sphincter of Oddi is a muscular valve that controls the flow of digestive juices (bile and pancreatic juice) through the ampulla of Vater into the second part of the duodenum. It is named after Ruggero Oddi.[1] The sphincter of Oddi is relaxed by the hormone cholecystokinin (CCK) via vasoactive intestinal polypeptide (VIP).[2]

Clinical significance[edit source | edit]

Opiates can cause spasms of the sphincter of Oddi, leading to increased serum amylase levels.

References[edit source | edit]

  1. ^ synd/2709 at Who Named It?
  2. ^ J Clin Invest. 1988 June; 81(6): 1920–1924.

Further reading[edit source | edit]