The airfield was perhaps the most secret airfield in the Second World War. It was home to the Special Duties Squadrons, No. 138, which dropped Special Operations Executive (SOE) agents and their supplies into occupied Europe, and No. 161, which specialised in personnel delivery and retrieval by landing in occupied Europe.
RAF Tempsford is very close to Little Gransden Airfield and can be clearly seen from flights climbing out from the westerly runway 28. Other active airfields nearby include the former RAF bases at Gransden Lodge and Bourn.
By 2002 part of the former Tempsford airfield was a concrete-making facility and some of the main airfield buildings had been turned into various commercial workshops. A nearby public footpath led to the end of a substantially intact runway and then on to Gibraltar Farm, the agents' final dispatch point. This barn contained several plaques and memorials to the agents, both men and women, who were flown from the airfield, many of whom were later killed after being captured and tortured. A memorial is also to be found in St Peter's Church, in the nearby village of Tempsford.
Andrée Borrel and Lise de Baissac (Odile), were the first female SOE agents to be parachuted into occupied France. They flew out from RAF Tempsford on 24 September 1942.