As associate editor at Collier's Weekly from 1933 to 1945, Reynolds averaged twenty articles a year. He also published twenty-five books, including The Wounded Don’t Cry, London Diary, Dress Rehearsal, and Courtroom, a biography of lawyer Samuel Leibowitz. He also published an autobiography, By Quentin Reynolds.
After World War II, Reynolds was best known for his libelsuit against right-wing Hearst columnist Westbrook Pegler, who called him "yellow" and an "absentee war correspondent". Reynolds, represented by noted attorney Louis Nizer, won $175,001 (approximately $1.5 million in 2014 dollars), at the time the largest libel judgment ever. The trial was later made into a Broadway play, A Case of Libel, which was twice adapted as TV movies.
In 1953, Reynolds was the victim of a major literary hoax when he published The Man Who Wouldn’t Talk, the supposedly true story of a Canadian war hero, George Dupre, who claimed to have been captured and tortured by German soldiers. When the hoax was exposed, Bennett Cerf, of Random House, Reynolds's publisher, reclassified the book as fiction.
Only the Stars are Neutral, Random House, 1942; Blue Ribbon Books, 1943
Dress Rehearsal: The Story of Dieppe, Random House, 1943
The Curtain Rises, Random House, 1944
Officially Dead: The Story of Commander C D Smith, USN; The Prisoner the Japs Couldn’t Hold No. 511 Random House, 1945 (Published by Pyramid Books under the title He Came Back in multiple printings in the 1960s and early 1970s.)
70,000 to 1 (Seventy Thousand to One); True War Adventure, 1946
The Wright Brothers, Pioneers of American Aviation, Random House Landmark Books, 1950
Courtroom; The Story of Samuel S Leibowitz, Farrar, Straus and Co, 1950
Custer's Last Stand, Random House, 1951
The Battle of Britain, Random House, 1953
The Amazing Mr Doolittle; A Biography of Lieutenant General James H Doolittle, Appleton-Century-Crofts, 1953
The Man Who Wouldn't Talk, 1953
I, Willie Sutton, Farrar, Straus and Young, 1953
The FBI, Random House Landmark Books, 1954
Headquarters, Harper & Brothers, 1955
The Fiction Factory; or, From Pulp Row to Quality Street; The Story of 100 years of Publishing at Street & Smith, Random House 1955
They Fought for the Sky; The Dramatic Story of the First War in the Air, Rinehart & Company, 1957
Minister of Death: The Adolf Eichmann Story (by Zwy Aldouby and Quentin James Reynolds), Viking 1960
Known But to God; The Story of the “Unknowns” of America’s War Memorials, John Day 1960
Britain Can Take It! (1940) “Quentin Reynolds, an American journalist, recorded this programme as a film dispatch from London.” Directors: Harry Watt and Humphrey Jennings; Photography: H Fowle and Frank ‘Jonah’ Jones; Narration: Quentin Reynolds