The song has been used and remixed by many artists and in many different arrangements. The most notable rendition in English was by pop singer Engelbert Humperdinck. In 2005, Michael Bublé performed the song as a duet with Nelly Furtado. There is an instrumental Latin version by Edgardo Cintron and The Tiempos Noventa Orchestra. The song was a 1962 Billboard Top 100 entry by Pat Boone.
Quando is the only Italian word normally retained in most English-language renditions of the song.
Pat Boone sang the starting piece in Italian but then carried on the rest of it in English, repeating every now and again some Italian words. The Italian words sung by Boone:
Dimmi quando tu verrai,
dimmi quando... quando... quando...
l'anno, il giorno e l'ora in cui
forse tu mi bacerai...
(Boone says "qui" which means "here" instead of "cui" which means "that").
Connie Francis, American pop singer of Italian origin sang in Italian in 1963
Rory Bremner parodied the song in the 2006 season of the Bremner, Bird and Fortune TV series, playing Gordon Brown and Tony Blair with the former asking when the then-prime minister would be leaving office.
It was also used in 2008 in the Fiat Punto advertisements, mimicking the "Portuguese Job".
In the 2006 film Superman Returns, the theme is performed by The Drifters in the elevator scene when Clark Kent and Lois Lane are in the middle of several people reading about the Man of Steel's return in the Daily Planet.