The series is broadcast in the United States on the cable channel TNT, and is produced by ABC Studios. It premiered on July 9, 2012.
On August 17, 2012, TNT renewed Perception for a second season, which aired from June 25, 2013, through March 18, 2014. On August 15, 2013, TNT renewed Perception for a third season,  which premiered on June 17, 2014.
On November 13, 2014, Perception was canceled after three seasons, however, the remaining five episodes will air starting in February 2015.
Dr. Daniel Pierce, a talented but eccentric neuropsychiatrist, is enlisted by the Federal Bureau of Investigation to assist in solving some of its most complex cases in Chicago. Dr. Pierce works closely with Special Agent Kate Moretti, a former student who recruited him to work with the FBI. Also on the team are Max Lewicki, Dr. Pierce's teaching assistant, and Natalie Vincent, a hallucination manifested as a result of his schizophrenia who also serves as his best friend.
Episodes typically begin with a scene of Pierce giving a lecture to his students about an aspect of the human brain that becomes significant within the plot of the episode. The episodes also typically end with observations to said students about the paradoxes of human perception.
Cast and characters
Eric McCormack as Dr. Daniel J. Pierce, a neuropsychiatrist and Davenport Award–winning neuroscienceprofessor at the (fictional) Chicago Lake Michigan University (CLMU), who is enlisted by the FBI as an expert consultant to assist on some of their most complex cases. Pierce's interest in neuroscience stems from his own long history of paranoid schizophrenia. His hallucinations sometimes enable him to pick out subtle clues in solving crimes. In the season 2 finale, Pierce quits CLMU after realizing that the faculty cares more about the school's image and benefactors than its education and moves to Paris.
Rachael Leigh Cook as Special Agent Katherine Rose "Kate" Moretti, Pierce's former student and the FBI agent who recruited him. Kate has a "tendency to go beyond the scope of the assigned investigation", which cost her a position in Washington, D.C. and caused her demotion back to Chicago. She had a crush on Pierce during her college years and is his most trusting ally.
Arjay Smith as Max Lewicki, Dr. Pierce's live-in teaching assistant, who helps him differentiate between real people and his schizophrenia-induced hallucinations. It is later revealed in the season 1 episode "Nemesis" that the two met when Lewicki was working as an orderly at the same psychiatric hospital Pierce had been confined for his mental illness. Pierce then asked Lewicki to come with him to Chicago on the promise of a teaching assistantship to help Max finish graduate school.
Kelly Rowan as Natalie Vincent, Pierce's imaginary best friend and adviser, who he realizes is based on someone he once saw at a college party in Michigan. Rowan also plays Dr. Caroline Newsome, Pierce's psychiatrist and the physical basis for Natalie.
Scott Wolf as Assistant U.S. Attorney Donald "Donnie" Ryan (season 3-, recurring season 2), Kate's ex-husband, who cheated on Kate with her best friend. He has recently transferred back to Chicago in an attempt to reignite his relationship with Kate.
Jonathan Scarfe as FBI Agent Roger Probert, Kate's former work partner, who is very cynical of Pierce's judgments.
On March 22, 2011, TNT green-lighted the series with an order of 10 episodes to air in the summer of 2012. Along with the series pickup, TNT announced that Alan Poul would not be continuing as an executive producer on the series beyond the pilot; they also announced that the character portrayed by McCormack had been renamed Daniel Pierce.
On August 17, 2011, TNT announced that production had commenced on the remaining nine episodes of Perception. The series is produced by ABC Studios.
On August 15, 2013, TNT announced it has renewed Perception for a third season of 15 episodes in 2014. Perception ended its season 2 summer run with episode 10 on August 27, 2013. The remaining four episodes of Season 2 aired in early 2014.
Casting announcements began in October 2010, with Eric McCormack first to be cast, McCormack portrays Dr. Geoffrey (later renamed Daniel) Pierce, "an eccentric neuroscientist who uses his unique outlook to help the federal government solve complex cases. With an intimate knowledge of human behavior and a masterful understanding of the mind, this quirky, crime-solving professor pulls lessons from an odd and imaginative view of the world." Next to join the series was Arjay Smith as Max Lewicki, "Pierce's teaching assistant, a perpetual student who has spent nine years in college and has had sixteen majors and not a single degree. His primary job is to keep Pierce in line and on task."Rachael Leigh Cook was next to be cast as Kate Rossi, "Pierce’s former student and the person responsible for recruiting him to work for the government."Kelly Rowan was the last actor to be cast, portraying Natalie Vincent, "Pierce’s best friend and every bit his intellectual equal."
Along with the announcement that production had started on the series, the network announced that Levar Burton had joined the series as a recurring guest star; he portrays Paul Haley, "a dean at the university." TNT also announced that the character portrayed by Cook had been renamed Kate Moretti.
On August 22, 2011, it was announced that Jamie Bamber had been cast in a recurring role as "a new professor who catches the eye of Kate Moretti." On October 14, 2011, TNT Public Relations announced that Freddy Rodriguez was cast in a two-episode role as "an eccentric ex-student of McCormack's Dr. Daniel Pierce."
On January 29, 2013, Scott Wolf joined the series in the major recurring role of Donnie, Kate's ex-husband who works as an Assistant U.S. Attorney. On February 13, 2014, Peter Coyote signed onto the season three guest role of James Alan Pierce, Daniel's father.