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POH may refer to:
- pOH, a measure of the concentration of hydroxide ions
- Power-on hours, the length of time, in hours, that electrical power is applied to a device
- Port Henry (Amtrak station), New York, United States; Amtrak station code POH
- A Player-Owned House in RuneScape, which is created by the Construction skill.
- Pilot's Operating Handbook, the operations manual for an aircraft, containing all checklists, specifications, and limitations for a given aircraft.