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OCS or Ocs may refer to:
- Officer Candidate School or Officer Cadet School, a training establishment in many countries where military officers are trained
Psychiatry and medicine
- Obsessive-compulsive syndrome or obsessive-compulsive disorder, a psychiatric anxiety disorder
- Oral corticosteroids, medication used for a variety of illnesses, chiefly through the mechanism of suppressing the immune system.
Science and technology
Schools and alumni associations