Myelopathy

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Myelopathy
Classification and external resources
ICD-10G95
ICD-9336.9
DiseasesDB22984
MeSHD013118
 
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Myelopathy
Classification and external resources
ICD-10G95
ICD-9336.9
DiseasesDB22984
MeSHD013118

Myelopathy refers to pathology of the spinal cord.[1] When due to trauma, it is known as spinal cord injury. When inflammatory, it is known as myelitis. Disease that is vascular in nature is known as vascular myelopathy.

Clinical signs and symptoms depend on which spinal cord level (cervical, thoracic or lumbar) is affected and the extent (anterior, posterior or lateral) of the pathology, and may include:

Differential diagnosis of chronic myelopathy is extensive.[2]

The presence and severity of myelopathy can be evaluated by means of Transcranial Magnetic Stimulation (TMS), a neurophysiological method that allows the measurement of the time required for a neural impulse to cross the pyramidal tracts, starting from the cerebral cortex and ending at the anterior horn cells of the cervical, thoracic or lumbar spinal cord. This measurement is called Central Conduction Time (CCT). TMS can aid physicians to:[3]

TMS can also help in the differential diagnosis of different causes of pyramidal tract damage.[5]

See also[edit]

References[edit]

  1. ^ "myelopathy" at Dorland's Medical Dictionary
  2. ^ Myelopathy differential diagnosis web site
  3. ^ Chen R, Cros D, Curra A, Di Lazzaro V, Lefaucheur JP, Magistris MR, Mills K, Rösler KM, Triggs WJ, Ugawa Y, Ziemann U. The clinical diagnostic utility of transcranial magnetic stimulation: report of an IFCN committee. Clin Neurophysiol. 2008 Mar;119(3):504-32.
  4. ^ Deftereos SN, et al. (April–June 2009). "Localisation of cervical spinal cord compression by TMS and MRI". Funct Neurol 24 (2): 99–105. PMID 19775538. 
  5. ^ Chen R, Cros D, Curra A, et al. (March 2008). "The clinical diagnostic utility of transcranial magnetic stimulation: report of an IFCN committee". Clin Neurophysiol 119 (3): 504–32. doi:10.1016/j.clinph.2007.10.014. PMID 18063409.