Metanx

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Metanx
Combination of
L-methylfolatevitamin
Pyridoxal 5'-phosphatevitamin
Methylcobalaminvitamin
Clinical data
AHFS/Drugs.commonograph
Legal status?
Identifiers
CAS number YesY
ATC code?
 N (what is this?)  (verify)
 
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Metanx
Combination of
L-methylfolatevitamin
Pyridoxal 5'-phosphatevitamin
Methylcobalaminvitamin
Clinical data
AHFS/Drugs.commonograph
Legal status?
Identifiers
CAS number YesY
ATC code?
 N (what is this?)  (verify)

Metanx is a medical food made by Pamlab that contains L-methylfolate (vitamin B9), methylcobalamin (vitamin B12) and pyridoxal 5'-phosphate (vitamin B6). It is a vitamin B supplement.

It is indicated for the treatment of endothelial dysfunction and hyperhomocysteinemia. In particular it has been shown to be an effective treatment for diabetic peripheral neuropathy[1][2], reducing symptoms of neuropathy, though not improving sensation.[3] It can also improve lower extremity ulcerations such as diabetic foot ulcers.[4]

Metanx contains the following active ingredients (per capsule):


References[edit]

  1. ^ Vascular Disease Management 2 (Suppl 6): 1S–9S. 2005. 
  2. ^ Yaqub, Basim A, et al. (1992). "Effects of methylcobalamin on diabetic neuropathy". Clinical Neurology and Neurosurgery 94: 105–111. 
  3. ^ Fonseca, Vivian (2013). "Metanx in type 2 diabetes with peripheral neuropathy: a randomized trial". The American journal of medicine 126 (2): 141–149. doi:10.1016/j.amjmed.2012.06.022. PMID 23218892. 
  4. ^ Boykin JV, Baylis C (2006). "Homocysteine--A Stealth Mediator of Impaired Wound Healing: A Preliminary Study". Wounds 18 (4): 101–116. 

External links[edit]