Mesaconic acid

From Wikipedia, the free encyclopedia - View original article

Mesaconic acid
Identifiers
CAS number498-24-8 YesY
Jmol-3D imagesImage 1
Properties
Molecular formulaC5H6O4
Molar mass130.10 g/mol
Density1.31 g/cm3
Melting point204-205 °C
Boiling point250 °C (decomp.)
 YesY (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references
 
Jump to: navigation, search
Mesaconic acid
Identifiers
CAS number498-24-8 YesY
Jmol-3D imagesImage 1
Properties
Molecular formulaC5H6O4
Molar mass130.10 g/mol
Density1.31 g/cm3
Melting point204-205 °C
Boiling point250 °C (decomp.)
 YesY (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Mesaconic acid is one of several isomeric carboxylic acids obtained from citric acid. It is the trans-isomer of citraconic acid. It is used as a fire retardant.

History[edit]

This acid was studied for the first time by Dutch chemist Jacobus H. van 't Hoff in 1874. Later American biochemist Horace Albert Barker and his team successfully isolated this acid from fermenting bacterium Clostridium tetanomorphum in 1950s. Further studies led him to discover this organic compound was involved in vitamin B12 coenzymes synthesis.

Recent studies revealed this acid is a competitive inhibitor of fumarate reduction.


References[edit]