Lufenuron

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Lufenuron
Lufenuron.png
Lufenuron-3D-balls.png
Identifiers
CAS number103055-07-8 N
PubChem71777
ChemSpider64813 YesY
KEGGD08150 N
ChEBICHEBI:39384 YesY
ATCvet codeQP53BC01
Jmol-3D imagesImage 1
Properties
Molecular formulaC17H8Cl2F8N2O3
Molar mass511.15 g/mol
Melting point174 °C (345 °F; 447 K)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N (verify) (what is: YesY/N?)
Infobox references
 
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Lufenuron
Lufenuron.png
Lufenuron-3D-balls.png
Identifiers
CAS number103055-07-8 N
PubChem71777
ChemSpider64813 YesY
KEGGD08150 N
ChEBICHEBI:39384 YesY
ATCvet codeQP53BC01
Jmol-3D imagesImage 1
Properties
Molecular formulaC17H8Cl2F8N2O3
Molar mass511.15 g/mol
Melting point174 °C (345 °F; 447 K)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N (verify) (what is: YesY/N?)
Infobox references

Lufenuron the active ingredient in the veterinary flea control medication Program™, and one of the two active ingredients in the flea, heartworm, and anthelmintic medicine milbemycin oxime/lufenuron (Sentinel™).

Lufenuron is stored in the animal's body fat and transferred to adult fleas through the host's blood when they feed. Adult fleas transfer it to their growing eggs through their blood, and to hatched larvae feeding on her excrement. It does not kill adult fleas.

Lufenuron, a benzoylurea pesticide, inhibits the production of chitin in insects. Without chitin, a larval flea will never develop a hard outer shell (exoskeleton). With its inner organs exposed to air, the insect dies from dehydration soon after hatching or molting (shedding its old, smaller shell).

Lufenuron is also used to fight fungal infections, since fungus cell walls are about ⅓ chitin[1] .

It has no toxic effects at any dosage on humans, other mammals or any animals not having hard shells (like shellfish and insects have).

Lufenuron is also sold as an agricultural pesticide for use against lepidopterans, eriophid mites, and western flower thrips. It is an effective antifungal in plants.

Because it is toxic to zooplankton,[2] Lufenuron was included in a biocide ban proposed by the Swedish Chemicals Agency. The ban was approved by the European Parliament on January 13, 2009.[3]

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