MD 20/20 is an American fortified wine with an alcohol content of 13%. The name is derived from the initials of its producer, Mogen David, but the drink is widely and affectionately known as "Mad Dog". Originally, 20/20 stood for 20 ounces of 20% alcohol by volume (ABV) although the wine is no longer sold in either 20 ounce bottles or at 20% ABV (the original "Red Grape Wine" flavor tops out at 18% ABV, though all other flavors are standardized at 13%).
Cisco is the brand name of a fortified wine produced by the Centerra Wine Company (a division of Constellation Brands) with varieties selling at 13.9%, 17.5% and 19.5% ABV. Cisco has a syrupy consistency and sweet taste; because of its color and bottle shape, it is frequently mistaken for a wine cooler. The Federal Trade Commission required the company to put labels on their bottles stating that Cisco is not a wine cooler, to change the shape and color of their containers, and to recall their advertising slogan "Takes you by surprise" 
Three popular brands in this category have been produced by the E & J Gallo Winery, and were a large part of that company's early success.
Ripple was a fortified wine produced by E & J Gallo Winery that was popular in the United States, particularly in the 1970s. Possessing a relatively low 11% ABV, it was originally marketed to "casual" drinkers. Due to its low price, it had a reputation as a drink for alcoholics and the destitute. It was popular among young drinkers, both underage and college students. The TV series Sanford & Son often referred to Ripple, as it was Fred Sanford's alcoholic beverage of choice.
Night Train Express, usually abbreviated to Night Train, typically contains 17.5% ABV. Night Train Express has been condemned by some civic leaders who think inexpensive high alcohol content drinks contribute to vagrancy and public drunkenness. Night Train no longer carries the Gallo logo or other indication of this source on the bottle, instead the vintner and bottler is printed as "Night Train Limited". It is also the origin of the Guns N' Roses song "Nightrain." Night Train also made an appearance in the Blues Brothers movie where it caused Jake's head to hurt.
Thunderbird, called The American Classic, is named for the Thunderbird Hotel in Las Vegas, Nevada. It is sold in 13% and 18% ABV varieties. It has been popular since the 1950s, when a popular rhythm and blues song went: "What's the word? Thunderbird / How's it sold? Good and cold / What's the jive? Bird's alive / What's the price? Thirty twice." It was once marketed in the United Kingdom as "The California Aperitif," and there is now a sister version, Thunderbird ESQ. It has also been the subject of many songs, three of which, recorded by ZZ Top, Seasick Steve, and They Might Be Giants, are aptly titled "Thunderbird." Influential Detroit garage rock band The Gories had a song entitled "Thunderbird ESQ." Rock band Clutch mentions the beverage in their song "Worm Drink." Townes Van Zandt sings a talking blues song reflecting on his experiences with Thunderbird entitled "Talking Thunderbird Blues". The song "Three Rings" by Insane Clown Posse also mentions the drink. An SCTV sketch from the late 1970s had John Candy's character of Johnny LaRue being served Thunderbird in a French restaurant when he was unable to afford the more expensive French wines which the menu listed. The single Sweet Gene Vincent by Ian Dury and the Blockheads mentions the drink in the line "Shall I mourn your decline with some Thunderbird wine and a black handkerchief." A 1971 song Hard Times by Baby Huey speaks of sleeping on motel floors and drinking Thunderbird.
Richards Wild Irish Rose is an alcoholic beverage produced by Centerra Wine Company, which is part of the Constellation Brands organization. It was introduced in 1954 and currently sells about two million cases annually. The brand is available in 13.9% and 18% alcohol by volume.
Buckfast Tonic Wine is a caffeine- and sugar-laced tonic wine with added alcohol, produced under license from an English monastery. It is very popular in Glasgow and Coatbridge in Scotland, but critics have blamed it for being one cause of social problems in Scotland. Some have called it "Wreck the Hoose Juice."
Stones Green Ginger Wine is a ginger-based wine, produced in the UK. It has an alcohol level of 13.7%.
Scotsmac is a blend of wine and whisky sold in the UK. It typically retails for about £4.00 (per 700ml bottle), significantly cheaper than its rival, Buckfast Tonic Wine.
Solntsedar was a Soviet brand of cheap fortified wine, marketed as "port wine," infamous for many severe cases of poisoning. Its production was cancelled after Mikhail Gorbachev's anti-alcohol laws.
777 is a Russian "port wine" similar to Solntsedar, but still in production. It is nicknamed "Three axes" after the shape of the digits, and has attained a near-legendary status among often-poor Soviet and Russian students and members of youth subcultures.
Bright's Pale Dry Select Sherry produced by Constellation Brands, is available in Canada and the Northern United States. Though nominally a sherry, it's been noted as having a high alcohol content by volume (20%), and has been characterized as very sweet  at 27 g/L of sugar. At $5–8 per bottle, it has a reputation as a potent value bumwine, though the intensely sweet flavor makes it difficult to consume unaccompanied.
An early reference to the problem of cheap and poorly made wines is in the "Report on Cheap Wines" in the 5 November 1864 issue of The Medical Times and Gazette. The author, in prescribing inexpensive wines for a number of ills, cautions against the "fortified" wines of the day, describing of one sample that he had tried:
When the cork was drawn it was scarcely tinted, and was a very bad one – a thing of no good augury for the wine. There was no smell of port wine. The liquid, when tasted, gave the palate half-a-dozen sensations instead of one. There was a hot taste of spirits, a sweet taste, a fruity taste like damsons, and an unmistakable flavor of Roussillon [an alternative name in France for wine made from the grape Grenache]. It was a strong, unwholesome liquor, purchased very dearly.
It is reported, however, that the popularity of cheap, fortified wines in the United States arose in the 1930s, as a product of Prohibition and the Great Depression:
Prohibition produced the Roaring Twenties and fostered more beer and distilled-spirit drinkers than wine drinkers, because the raw materials were easier to come by. But fortified wine, or medicinal wine tonic—containing about 20 percent alcohol, which made it more like a distilled spirit than regular wine—was still available and became America's number one wine. Thunderbird and Wild Irish Rose, to name two examples, are fortified wines. American wine was soon more popular for its effect than its taste; in fact, the word wino came into use during the Depression to describe those unfortunate souls who turned to fortified wine to forget their troubles.
—Kevin Zraly, Kevin Zraly's American Wine Guide (2006) p. 38.
Concerns and media attention
While overtaken somewhat in the low-end alcoholic drink market by sweetened malt beverages in recent years, the appeal of cheap fortified wines to the poor and homeless has often raised concerns:
Community groups in Los Angeles, San Francisco, Seattle, and Portland have urged makers of fortified wines such as Wild Irish Rose and E & J Gallo's Thunderbird and Night Train brands to pull their products from the shelves of liquor retailers in skid row areas. In Nashville, Tennessee, one liquor store owner told Nashville Business Journal reporter Julie Hinds that police warned him to stop selling his biggest selling product, Wild Irish Rose, because it encouraged homeless people to linger in the area.
—Janice Jorgensen, Encyclopedia of Consumer Brands: Consumable Products (1993), p. 492.
In 2005, the Seattle City Council asked the Washington State Liquor Control Board to prohibit the sale of certain alcohol products in an impoverished "Alcohol Impact Area". Among the products sought to be banned were over two dozen beers, and six wines: Cisco, Gino's Premium Blend, MD 20/20, Night Train, Thunderbird, and Wild Irish Rose. The Liquor Control Board approved these restrictions on 30 August 2006. The cities of Tacoma, Washington and Spokane, Washington also followed suit in instituting "Alcohol Impact Areas" of their own following Seattle's example.