Loteprednol

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Loteprednol etabonate
Loteprednol etabonate.svg
Systematic (IUPAC) name
Chloromethyl 17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-17-carboxylate
Clinical data
AHFS/Drugs.comMicromedex Detailed Consumer Information
MedlinePlusa606003
Legal status
Identifiers
CAS number82034-46-6 YesY
ATC codeS01BA14
PubChemCID 444025
DrugBankDB00873
ChemSpider392049 N
UNIIZ8CBU6KR16 N
KEGGD01689 YesY
ChEMBLCHEMBL1201389 N
Chemical data
FormulaC24H31ClO7 
Molecular mass466.951 g/mol
 N (what is this?)  (verify)
 
  (Redirected from Lotemax)
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Loteprednol etabonate
Loteprednol etabonate.svg
Systematic (IUPAC) name
Chloromethyl 17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-17-carboxylate
Clinical data
AHFS/Drugs.comMicromedex Detailed Consumer Information
MedlinePlusa606003
Legal status
Identifiers
CAS number82034-46-6 YesY
ATC codeS01BA14
PubChemCID 444025
DrugBankDB00873
ChemSpider392049 N
UNIIZ8CBU6KR16 N
KEGGD01689 YesY
ChEMBLCHEMBL1201389 N
Chemical data
FormulaC24H31ClO7 
Molecular mass466.951 g/mol
 N (what is this?)  (verify)

Loteprednol (as the ester loteprednol etabonate) is a corticosteroid used in ophthalmology. Marketed by Bausch and Lomb as Lotemax in the U.S., ocular applications for this drug include the treatment of inflammation of the eye due to allergies (according to the prescription information sheet), as well as chronic forms of keratitis (e.g.: adenoviral and Thygeson’s keratitis), vernal keratoconjunctivitis, pingueculitis, and episcleritis. The drug has little or no effect on intraocular pressure.

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