This list of dog diseases is a continuously updated selection of diseases and other conditions found in the dog. Some of these diseases are unique to dogs or closely related species, while others are found in other animals, including humans. Not all of the articles listed here contain information specific to dogs. Articles with non-dog information are marked with an asterisk (*)
Animal InfectionsRabies (hydrophobia) is a fatal viral disease that can affect any mammal, although the close relationship of dogs with humans makes canine rabies a zoonotic concern. Vaccination of dogs for rabies is commonly required by law. Please see the article dog health for information on this disease in dogs.
Canine parvovirus is a sometimes fatal gastrointestinal infection that mainly affects puppies. It occurs worldwide.
Canine coronavirus is a gastrointestinal disease that is usually asymptomatic or with mild clinical signs. The signs are worse in puppies.
Canine distemper is an often fatal infectious disease that mainly has respiratory and neurologic signs.
Canine influenza is a newly emerging infectious respiratory disease. Up to 80 percent of dogs infected will have symptoms, but the mortality rate is only 5 to 8 percent.
Blastomycosis* is a fungal disease caused by Blastomyces dermatitidis" that affects both dogs and humans. Dogs are ten times more likely to be infected than humans. The disease in dogs can affect the eyes, brain, lungs, skin, or bones.
Coccidioidomycosis* is a fungal disease caused by Coccidioides immitis or Coccidioides posadasii that affects a variety of species, including dogs. In dogs signs of primary pulmonary disease include a cough, fever, weight loss, anorexia, and lethargy. Disseminated disease occurs when the fungus has spread outside of the lungs and may include clinical signs such as lameness, pain, seizures, anterior uveitis, and localized swelling. Diagnosis of Valley Fever may include multiple tests, including serology and radiology. According to a study performed in the Tucson and Phoenix area, 28% of dogs will test positive for exposure to the fungus by two years of age, but only 6% of the dogs will be ill with clinical disease. There is an increased risk of infection associated with amount of time spent outdoors, a larger roaming space accessed by the dog, and increasing age.
Cryptococcosis* is a fungal disease caused by Cryptococcus neoformans that affects both dogs and humans. It is a rare disease in dogs, with cats seven to ten times more likely to be infected. The disease in dogs can affect the lungs and skin, but more commonly the eye and central nervous system.
Sporotrichosis is a fungal disease caused by Sporothrix schenckii that affects both dogs and humans. It is a rare disease in dogs, with cat and horse infections predominating in veterinary medicine. The disease in dogs is usually nodular skin lesions of the head and trunk.
Aspergillosis* is a fungal disease that in dogs is caused primarily by Aspergillus fumigatus. Infection is usually in the nasal cavity. Typical signs in dogs include sneezing, nasal discharge, bleeding from the nose, and ulcerations of the nose.
Pythiosis is a disease cause by a water mould of the genus Pythium, P. insidiosum. It occurs primarily in dogs and horses, but can also affect humans. In dogs it affects the gastrointestinal system and lymph nodes, and rarely the skin.
Mucormycosis is a collection of fungal and mold diseases in dogs including pythiosis, zygomycosis, and lagenidiosis that affect the gastrointestinal tract and skin.
Chiggers*, also known as harvest mites, can cause itching, redness and crusting in dogs.
Mange in dogs include demodectic mange and sarcoptic mange. Demodectic mange is caused by Demodex canis. Signs include hair loss, redness, and scaling, and is not contagious to humans!. Sarcoptic mange is caused by Sarcoptes scabiei canis. Signs include intense itching and scaling, and is contagious to humans.
Demodex also known as demodicosis live in small numbers in the sebaceous glands and hair follicles. These mites can cause inflammation and hair loss, they can also lead to secondary bacterial infections such as fever, lethargy, and enlarged lymph nodes.
Sarcoptes scabiei is a mite that burrows into humans and dogs alike and causes scabies. There is only one symptom, itchy and red skin.
Gnathostoma is a disease from mammal feces and undercooked seafood.
Skeletal and muscular disorders
Osteoarthritis*, also known as degenerative arthritis, is a common condition in dogs characterized by progressive deterioration of articular cartilage in the joints of the limbs. It can cause a great deal of pain and lameness. Treatment options include medications such as NSAIDs, corticosteroids, and joint fluid modifiers such as glycosaminoglycans. Other treatments include surgery, massage, warm compresses, chiropractic, and acupuncture.
Hip dysplasia is an inherited disease in dogs that is characterized by abnormal development of the acetabulum and head of the femur. It is more common in large breeds.
Elbow dysplasia is a condition found more commonly in large breeds. It incorporates several different hereditary conditions of the elbow, including osteochondritis of the medial condyle of the humerus, fragmentation of the medial coronoid process of the ulna, and ununited anconeal process of the ulna.
Luxating patella is a medial or lateral displacement of the patella, or kneecap. It is strongly suspected to be inherited, but can also result from trauma. It is more common in smaller breeds of dogs 
Osteochondritis dissecans (OCD) is separation of immature articular cartilage from underlying bone. It is caused by osteochondrosis, which is characterized by abnormal endochondral ossification of epiphyseal cartilage. It is most commonly seen in the stifle, elbow, shoulder, and hock.
Panosteitis is a common disease of unknown cause that causes pain and a shifting leg lameness in medium and large breed dogs. It affects the long bones of the hind and forelimbs.
Legg-Calvé-Perthes syndrome, also known as Perthes disease or aseptic necrosis of the femoral head, is characterized by a deformity of the head of the femur and hip pain. It occurs in small breed puppies.
Back pain* in dogs, particularly in long-backed breeds, such as Basset Hounds and Dachshunds, is usually caused by intervertebral disk disease. It is caused by degeneration and protrusion of the disk and compression of the spinal cord. It occurs most commonly in the cervical and thoracolumbar regions. Signs include back pain, hind limb weakness, and paralysis.
Congenital vertebral anomalies, including butterfly, block, and transitional vertebrae, and hemivertebrae, are a collection of malformations of the spine in animals. Most are not clinically significant, but they can cause compression of the spinal cord by deforming the vertebral canal or causing instability.
Hypertrophic osteopathy is a bone disease secondary to disease in the lungs. It is characterized by new bone formation on the outside of the long bones.
Hypertrophic osteodystrophy is a bone disease in rapidly growing large breed dogs. Signs include swelling of the metaphysis (the part of the bone adjacent to the joint), pain, depression, loss of appetite, and fever. The disease is usually bilateral in the limb bones.
Spondylosis*, known as spondylosis deformans in dogs, is growth of osteophytes on the ventral and lateral surfaces of the vertebral bodies. It is usually an incidental finding on radiographs and rarely causes symptoms.
Masticatory muscle myositis (MMM) is an inflammatory disease in dogs affecting the muscles of the jaw. Signs include swelling of the jaw muscles and pain on opening the mouth. In chronic MMM there is atrophy of the jaw muscles, and scarring of the masticatory muscles due to fibrosis may result in inability to open the mouth (trismus).
von Willebrand disease* is an inherited, common disease found in both dogs and humans. It is characterized by a deficiency of a protein called von Willebrand factor, which is involved in blood clotting. The disease varies from mild to severe, depending on the amount of von Willebrand factor present in the dog. Signs include spontaneous bleeding and excessive bleeding following surgery, injury, or during an estrous cycle.
Thrombocytosis* is a condition characterized by an excess of platelets. Most cases are physiologic (caused by exercise) or reactive (secondary to some cancers, blood loss, or certain drugs). Rarely the condition is caused by a primary bone marrow disorder. In this last case, the platelets may not function normally, causing the blood to not clot properly.
Degenerative mitral valve disease* is a common cause of congestive heart failure in dogs, especially small, older dogs. The leaflets of the valve become thickened and nodular, leading to mitral valve regurgitation and volume overload of the left side of the heart. Cavalier King Charles Spaniels have an inherited form of this disease.
Congestive heart failure* is any heart disease that results in the inability to put out enough blood to meet the dog's needs. It can be caused by the above two diseases, heat stroke, electric shock, injury, infection, developmental heart defects, or high blood pressure. Signs depend on which side of the heart is affected. Left-sided heart failure may result in coughing and difficulty breathing from a build-up of fluid in the lungs (pulmonary edema) and fainting. Right-sided heart failure may result in a build-up of fluid in the abdomen (ascites), fluid around the lungs (pleural effusion), or peripheral edema.
Ventricular septal defect* is a hole in the division between the heart ventricles. It is a congenital disease in dogs. There usually are no signs in dogs except for a heart murmur.
Atrial septal defect* is a hole in the division between the heart atria. It is an uncommon condition in dogs. Most are not clinically significant, but large defects may cause heart failure, cyanosis, and exercise intolerance.
Heart valve dysplasia (including mitral and tricuspid valve dysplasia) is a congenital heart defect in dogs. Dysplasia of the mitral and tricuspid valves - also known as the atrioventricular (AV) valves - can appear as thickened, shortened, or notched valves.
Pericardial effusion* is a collection of fluid in the pericardium. It is usually serous (clear or yellow fluid) or serosanguinous (bloody fluid). Serious accumulation is caused by heart failure, peritoneopericardial diaphragmatic hernias, uremia, pericardial cysts, or hypoalbuminemia. Serosanguinous accumulation can be caused by cancer, usually hemangiosarcoma, idiopathic disease, trauma, clotting disorders, or left atrial rupture. Rarely pericardial effusion can be caused by infection and consist of pus. Drainage of the fluid is the ideal treatment.
Trapped Neutrophil Syndrome* is an autosomal recessive disease which results in mature neutrophils being unable to migrate from the bone marrow into the blood. Affected pups suffer from chronic infections and failure to thrive. Other symptoms can include stunted growth and a ferret like facial appearance. The disease is common in Border collies.
Polyneuropathy is a collection of peripheral nerve disorders that often are breed-related in dogs. Polyneuropathy indicates that multiple nerves are involved, unlike mononeuropathy. Polyneuropathy usually involves motor nerve dysfunction, also known as lower motor neuron disease.
Scotty Cramp is a disease in Scottish Terriers causing spasms and hyperflexion and hyperextension of the legs. It is caused by a disorder in serotonin metabolism that causes a deficiency of available serotonin.
Cauda equina syndrome*, also known as degenerative lumbosacral stenosis, in dogs is a compression of the cauda equina by a narrowing of the lumbosacral vertebral canal. It is most commonly seen in German Shepherd Dogs. Signs include pain, weakness, and rear limb muscle atrophy.
Coonhound paralysis is a type of polyradiculoneuritis seen in Coonhounds. The cause has been related to a raccoon bite. Signs include rear leg weakness progressing rapidly to paralysis, and decreased reflexes.
Tick paralysis* is a disease in dogs caused by a neurotoxin found in the saliva of female ticks. Dermacentor species predominate as a cause in North America, while Ixodes mainly causes the disease in Australia. There is a gradual onset of signs, which include incoordination progressing to paralysis, changed voice, and difficulty eating.
Granulomatous meningoencephalitis (GME) (including Pug Dog encephalitis and other noninfectious causes of meningoencephalitis) is an inflammatory disease of the central nervous system of dogs. It is a form of meningoencephalitis. The disease is more common in female toy dogs of young and middle age.
Facial nerve paralysis* is most commonly caused in dogs by trauma, otitis media, or as an idiopathic condition. Signs include an inability to blink, drooping of the ear, and drooping of the lips on the affected side, although in chronic conditions fibrosis occurs and the ear and lips may appear to be in an abnormal position.
Entropion (eyelid folding inward) is a common condition in dogs, especially the Chow Chow, Shar Pei, St. Bernard, and Cocker Spaniel. Upper lid entropion involves the eyelashes rubbing on the eye, but the lower lid usually has no eyelashes, so hair rubs on the eye. Surgical correction is used in more severe cases.
Distichia (including ectopic cilia) is an eyelash that arises from an abnormal spot on the eyelid. Distichiae usually cause no symptoms because the lashes are soft, but they can irritate the eye and cause tearing, squinting, inflammation, and corneal ulcers.
Trichiasis in dogs is hair from the eyelid growing in the wrong direction and rubbing on the eye, causing irritation. It usually occurs at the lateral upper eyelid, especially in the English Cocker Spaniel.
Cataracts* are an opacity in the lens of the eye. Most cataracts in dogs are caused by a genetic predisposition, but diabetes mellitus is also a common cause. The only effective treatment is surgical removal. At present, a new drug is being tested that may prevent the formation of cataracts in diabetic dogs and to reverse early cataract formation.
Lens luxation is a displacement of the lens from its normal position. Terrier breeds are predisposed.
Nuclear sclerosis is a consistent finding in dogs greater than seven years old. Nuclear sclerosis appears as a bilateral bluish-grey haziness at the nucleus, or center of the lens. Many people get this confused with Cataracts, and that is not the case. Many people also think the dog loses its vision, but the dogs can actually see quite well.
A young Airedale Terrier, suffering from a congenital retina condition and subsequent cataract formation, and totally blind by the age of six years.
Progressive retinal atrophy (PRA) is a genetic disease of the retina that occurs bilaterally and is seen in certain breeds of dogs. It causes progressive vision loss culminating in blindness.
Retinal dysplasia is an eye disease affecting the retina of dogs. It is usually a nonprogressive disease and can be caused by viral infections, drugs, vitamin A deficiency, or genetics. Retinal dysplasia is characterized by folds or rosettes (round clumps) of the retinal tissue.
Corneal dystrophy is a condition characterized by bilateral, noninflammatory opacity of the cornea. It appears as grayish white lines, circles, or clouding of the cornea. Corneal dystrophy can also have a crystalline appearance.
Cherry eye is the term used to refer to canine nictitans gland prolapse, a common eye condition in various dog breeds where the gland of the third eyelid prolapses and becomes visible.
Canine Glaucoma* is an increase of pressure within the eye. It is a common condition in dogs. It can be caused by abnormal development of the drainage angle of the eye, lens luxation, uveitis, or cancer. Cocker Spaniels, Poodles, and Basset Hounds are predisposed.
Ocular Melanosis (OM) is a disease of the eye which in dogs is almost found exclusively in the Cairn Terrier. The disease is caused by an increase of melanocytes in the iris, sclera, and surrounding structures.
Keratoconjunctivitis sicca (dry eye) is common in dogs. Symptoms include eye redness, a yellow or greenish discharge, ulceration of the cornea, pigmented cornea, and blood vessels on the cornea.
Eye proptosis is a condition resulting in forward displacement and entrapment of the eye from behind by the eyelids. It is a common result of head trauma in dogs. Most commonly it occurs in brachycephalic (short nosed) breeds.
Deafness* in dogs can be either acquired or congenital. Predisposing factors for acquired deafness include chronic infection, use of certain drugs, and most commonly, age-related changes in the cochlea. Congenital deafness can be genetic, seen sometimes in dogs with merle or white coats, or caused by in utero damage from infections or toxins.
Fly strike dermatitis occurs at the tip and folds of the ear in dogs. It is caused by bites of the stable fly, Stomoxys calcitrans.
Atopy* is an allergy to a substance with which the dog is not necessarily in direct contact. It is a type I hypersensitivity to a substance that is inhaled or absorbed through the skin. Up to 10 percent of dogs are affected. It is common in dogs, especially seen in breeds such as Labrador Retrievers, Golden Retrievers, and Shih Tzus. The most common symptom is itching. Affected areas include the underside, the face, the feet, and the ears.
Food allergy* in dogs is commonly manifested as itching, especially of the face, paws, and the underside. Skin testing has proved unreliable, and a trial of a hypoallergenic diet is usually used for diagnosis.
Follicular dysplasia is a genetic disease of dogs causing alopecia, or hair loss. It is caused by hair follicles that are misfunctioning due to structural abnormality.
Dermoid sinus a genetic, autosomal skin condition in dogs. It can appear as single or multiple lumps on the dorsal midline.
Lick granuloma also known as acral lick dermatitis, is a skin disorder in dogs resulting from an urge to lick the lower portion of the leg. The lesion from the incessant licking is a thickened, firm, oval plaque.
Pemphigus is an uncommon autoimmune skin disease. The most common form in dogs is pemphigus foliaceus, which manifests as erosions and crusting of the skin and mucocutaneous junctions. Pemphigus vulgaris is more rare and manifests as blister-like lesions in the mouth and at mucocutaneous junctions. Bullous pemphigoid is most commonly seen in Dobermanns and Collies and appears as a scald-like lesion of the groin.
Dermal fragility syndrome, also known as Ehlers-Danlos-like syndrome, is a rare condition in dogs characterized by increased skin elasticity and poor wound healing. There appears to be a genetic basis for the disease.
A mast cell tumor (mastocytoma) is a type of tumor normally found in the skin of dogs. It can also invade the subcutis and spread to the liver, spleen, or bone marrow.
Lymphoma (lymphosarcoma) is a malignant cancer that is classified by location, cell type, and histological grade. The most common form in dogs is multicentric, involving the lymph nodes.
Fibrosarcoma is a malignant tumor that most commonly occurs in the mouth in dogs, and less commonly in the skin, subcutis, and bones.
Squamous cell carcinoma* is a malignant tumor in dogs that most commonly occurs in the oral cavity, including the tongue, tonsils, and gingiva. Squamous cell carcinoma accounts for 5 percent of skin tumors in dogs, and are the most common tumor of the toe. Dogs with unpigmented skin on the nose may develop this cancer from long-term sun exposure.
Perianal gland tumor (also called hepatoid tumor) is a type of tumor found near the anus in dogs that arises from specialized glandular tissue found in the perineum. They are most common in intact (not neutered) male dogs.
Melanomas* account for four to six percent of skin tumors in dogs and are usually benign. They are the second most common tumor of the toe and are malignant in this location. Malignant melanoma is also a common oral tumor in dogs. Malignant tumors most commonly spread to the lymph nodes and lungs.
Plasmacytomas* are common skin tumors in dogs that derive from B lymphocytes. Most are benign. Tumors of B lymphocyte origin that affect the bone marrow and are diffuse throughout the body are malignant and are called multiple myeloma*.
Prostate cancer* is rare in dogs and occurs in both intact and neutered animals. It is malignant. The most common type is adenocarcinoma. Signs include blood in the urine and straining to urinate or defecate. It most commonly spreads to bone and the lungs.
Mammary tumors in dogs are potentially benign or malignant. They occur most commonly in non-spayed females or female that were spayed later in life.
Nasal cancer makes up one to two percent of all types of tumors in dogs. Adenocarcinoma is the most common type, followed by sarcomas such as fiborsarcoma and chondrosarcoma. Signs include sneezing and bloody nasal discharge.
Thyroid cancer* is rare and usually nonproductive in dogs (unlike in cats, in which it causes hyperthyroidism). One-third of thyroid tumors are small benign adenomas; the rest are malignant carcinomas, usually large and invasive.
Gastrointestinal cancer* is uncommon in dogs. The most common type is lymphoma. Nonlymphomatous esophageal cancer is especially rare, the most common types being squamous cell carcinoma, adenocarcinoma, leiomyosarcoma, and osteogenic sarcoma associated with the parasite Spirocerca lupi. Nonlymphomatous stomach cancer is usually an adenocarcinoma, and nonlymphomatous intestinal cancer is usually polyps, adenomas, adenocarcinomas, leiomyosarcomas, and leiomyomas.
Pica is an appetite for, or the behavior of eating, non-nutritive substances (e.g., sand, coal, soil, chalk, paper etc.). Pica can be dangerous to dogs, with a risk from eating dirt near roads that existed prior to the phaseout of tetraethyllead in gasoline or prior to the cessation of the use of contaminated oil (either used, or containing toxic PCBs) to settle dust. In addition to poisoning, there is a risk of gastro-intestinal obstruction or tearing in the stomach or blockage of the esophagus.
Sensitivity to anaesthesia can occur in any breed, but sighthounds have been the breeds most documented to have anesthetic concerns. Sighthounds are known to have prolonged recovery times from ultra short-acting thiobarbiturates such as thiopental.
Heat stroke can occur in dogs, especially in flat-faced breeds such as the Bulldog or in giant breeds. Breed, lack of water, exercise, and high ambient temperature predispose dogs to heat stroke. Signs include vomiting, diarrhea, collapse, difficulty breathing, and body temperature approaching 42°C to 43°C. Treatment includes cooling the dogs with wet towels and fans, intravenous fluid therapy, and other supportive care. If a dog's temperature begin to drop to around 40°C, stop the cooling process. Once a dog’s body begins to cool, it can drop quickly and getting them too cool can create different problems. Allow the dog only a couple of laps of water until their temperature begins to drop to a more normal level. Do not allow a dog to gulp large quantities of water. If a dog is panting excessively and then drinks a lot of water, he will swallow large amounts of air with the water and this can cause an equally life-threatening case of bloat in their stomach.
Foxtails and sandburs can penetrate the lining of the mouth or skin and migrate, causing abscesses and draining tracts.
Shown here are the pituitary gland: (Acromegaly, a form of Cushing's disease, a form of Diabetes Insipidus, atypical Addison's diesase), the ovary for females: (Secondary Diabetes, Transient Diabetes), the adrenal gland: (a form of Cushing's disease, typical Addison's disease), the thyroid gland: (Hypothyroidism), and the pancreas: (Diabetes Mellitus).
Hyperthyroidism* is rare in dogs. The most common cause is thyroid carcinoma, a malignant tumor. Signs include weight loss, increased appetite, and enlargement of the thyroid gland.
Hypothyroidism is the most common endocrine disease in dogs. It can be caused by autoimmune destruction (lymphocytic thyroiditis) or idiopathic atrophy of the thyroid gland. These two causes are responsible for over 95% of the hypothyroidism cases in dogs. Signs include decreased appetite, weight gain, hair loss, dry skin/coat, skin that is cold to the touch, recurring skin infections, and lethargy. The dog may also seek out warm places to lie. The symptoms of hypothyroidism are shared with many other medical conditions; it may not be the first thought when a diagnosis is made. Symptoms may not appear until 75% or more of the gland is non-functional. In less than 10% of hypothyroidism cases, the problem is not with the thyroid gland itself, but with the pituitary gland in the brain. The pituitary gland produces a thyroid stimulating hormone (TSH); without this hormone to signal the thyroid gland to produce its thyroid hormone, the thyroid gland remains inactive. Treatment is with oral thyroid hormone supplementation. Lack of enough iodine in the diet can produce a form of hypothyroidism; without the proper amount of it, the thyroid gland fails to produce enough thyroid hormone.Myxedema coma is a rare but serious aspect of the disease that is a medical emergency.
Addison's disease, also known as hypoadrenocorticism, is a reduction of production of glucocorticoids and mineralocorticoids by the adrenal glands. There is more familiarity with the glucocortcoids, such as cortisol; mineralcorticoids control the amount of potassium, salt and water in the body. It is most commonly caused by destruction of adrenal tissue, probably by autoimmune disease. Signs include increased drinking and urination, vomiting, diarrhea, collapse, shivering and weight loss; at times neither the causes nor symptoms are especially specific. Because of this it is sometimes referred to as "the Great Mimic" or "the Great Imitator". It is possible not to see any symptoms of the disease until the adrenal cortex is 90% dysfunctional. Addison's can occur when regular steroid use is abruptly discontinued; during their use, the system the adrenal gland does not function at 100%. The system senses sufficient levels of these hormones in the body and does not signal for their production. Tapering the medication off gradually allows them to return to full production after discontinuation. About 35% of canine Addison's patients are not diagnosed until they experience an Addisonian crisis, which outwardly appears to be a "classic" shock and is a medical emergency.Hyperkalemia can develop and cause severe bradycardia. Only typical Addison's patients have the risk of Addisonian crisis due to the lack of mineralocorticoids. Treatment is with supplementation of mineralocorticoids in daily pills or a monthly injection. The atypical form and the form caused by abrupt withdrawal of steroids do not need mineralocorticoids. Glucocorticoids are usually supplemented with oral prednisone.
Cushing's syndrome, also known as hyperadrenocorticism, is a condition characterized by an increase in glucocorticoids secreted by the adrenal glands. About 85 percent of cases are caused by a tumor in the pituitary gland, while 15 percent are caused by an adrenal tumor. The pituitary gland produces a hormone that signals the adrenal gland to produce cortisol; a tumor can cause it to produce the adrenal-stimulating hormone even when it is not needed. Signs include increased appetite, increased drinking and urination, a pot-bellied appearance, muscle weakness, and lethargy. Cushing's can be caused by overuse of steroid medications; in some cases, stopping the medication is enough to solve the problem. Diagnosis can be difficult as there are no tests with both high sensitivity and specificity. Treatments inclulde mitotane, trilostane,ketoconazole, or selegiline. Surgery is used in some cases of adrenal tumors.
Diabetes insipidus* in dogs and cats can be central, caused by a lack of antidiuretic hormone (ADH), or nephrogenic, caused by a lack of response of the kidneys to ADH. Neither form is common. Central diabetes insipidus (CDI) is usually idiopathic, but can also be caused by head trauma or tumors of the brain. Nephrogenic diabetes insipidus (NDI) can be primary (hereditary) or secondary (caused by a variety of metabolic and renal diseases, including Cushing's syndrome and pyometra). Because the disease is characterized by an inability to concentrate urine, the most common sign is increased drinking and urinating. Treatment of CDI is to use desmopressin, a synthetic analog of ADH. Treatment of NDI is to treat the underlying cause, if any.
Acromegaly (also known as hypersomatotropism) is a hormonal condition resulting from over-secretion of the growth hormone somatotropin from the pituitary gland. The hormone is responsible for growth from birth to adulthood. Normally in adulthood, the growth plates of the bones close and the secretion of the hormone slows considerably. Because the bone plates close when entering maturity, the continued growth of acromegaly is not of normal proportions. Most canine sufferers of the disease are unspayed females but the condition can come about with use of medications containing progesterone. Acromegaly patients often also have diabetes mellitus. There is a transient form of acromegaly which can affect females at the diestrus portion of the reproductive cycle. This condition is brought about by the mammary glands excreting excess growth hormone, which is triggered by progesterone from the ovaries. As with non-transient acromegaly, spaying is necessary. The symptoms can include overgrowth or enlargement of gums with wide spaces between teeth, increased drinking, increased urination, thickening of the skin and skin folds, enlargement of the tongue and excessive panting. Acromegaly is also possible from a somatotroph adenoma. The hormone somatostatin can also be useful in treatment. Since hypothyroidism is connected with the release of excess growth hormone, hypothyroidism can be mistaken for acromegaly.
Bloat*, also known as torsion or gastric dilatation volvulus, is a serious condition in which the stomach swells with air (gastric dilatation), sometimes twisting on itself (volvulus). Deep-chested breeds are at a higher risk of bloating. Factors that predispose dogs to this condition are intestinal foreign bodies, intestinal cancer, intussusception, and other intestinal diseases. It has a poor prognosis.
Foreign body is an object foreign to the body that becomes lodged in the gastrointestinal tract (or other part of the dog). Dogs are susceptible to gastrointestinal obstruction due to their ability to swallow relatively large objects and pass them through the esophagus. Foreign bodies most commonly become lodged in the stomach because of the inability to pass through the pyloric sphincter, and in the jejunum.
Anal fistulae*, known as perianal fistulae in dogs, are most common in German Shepherd Dogs. They are characterized by draining tracts in the skin around the anus. The cause is unknown. Surgical treatment is common, but recently use of cyclosporine in combination with ketoconazole has been shown to be effective.
Bilious vomiting syndrome is vomiting in response to bile-induced inflammation of the stomach. Bile salts interfere with the gastric mucosal barrier, allowing acid to irritate the stomach lining and cause gastritis.
Intussusception* is characterized by telescoping of one part of the gastrointestinal tract into another part, forming an obstruction. It is most common in dogs six to eight months old. Surgery is necessary for treatment.
Hemorrhagic gastroenteritis is a disease of dogs characterized by sudden vomiting and bloody diarrhea. The symptoms are usually severe and can be fatal if not treated. It is most common in young adult dogs of any breed, but especially small dogs such as the Toy Poodle and Miniature Schnauzer.
Urinary incontinence* is leakage of urine, usually due to incompetence of the urethral sphincter in adult dogs and ectopic ureter (a congenital condition in which the ureter enters the urinary tract posterior to the urethral sphincter) in puppies. In adult dogs it is most commonly seen in large spayed females. The lack of estrogens in spayed dogs has been linked to development of incontinence. Replacement of estrogens, phenylpropanolamine, and surgery have all been used for treatment.
False pregnancy*, or pseudocyesis, is a common condition in female intact dogs. Signs include swelling of the mammary glands, lactation, not eating, and "mothering" small objects.
Pyometra is an infection of the uterus. It is a common and potentially fatal condition in dogs. The main risk period for a female is for eight weeks after her peak standing heat (or estrus cycle) has ended.
Umbilical hernia* is a failure of the umbilical ring of the abdominal wall to close. They are very common and can be caused by genetics or by traction on the umbilical cord or by the cord being cut too close to the body. They are corrected by surgery.
Inguinal hernia* is a protrusion of abdominal contents through the inguinal canal. They are corrected through surgery.
Mouse and rat poison* ingestion is common in dogs. Most rodenticides in the United States are anticoagulant by depleting Vitamin K. This type is the most frequent cause of poisoning in pets. Third generation products contain brodifacoum or bromadiolone and are toxic after a single ingestion. Signs include spontaneous and excessive bleeding internally and externally. Treatment is with Vitamin K supplementation. Other rodenticides may contain cholecalciferol which causes hypercalcemia and leads to heart and kidney problems. Newer rodenticides may contain bromethalin which causes central nervous system signs such as seizures, muscle tremors, and depression.
Insecticides* used in dogs for fleas and ticks commonly contain either organophosphates or carbamates. they can be absorbed through the skin, conjunctiva, gastrointestinal tract, and lungs. Organophosphates inhibit acetylcholinesterase irreversibly and carbamates inhibit cholinesterase reversibly. Toxicity occurs through overdosage with an appropriate product or use of an agricultural product. Signs for both include hypersalivation, vomiting, lethargy, tremors, difficulty walking, weakness, and death.
Chocolate is a common cause of poisoning in dogs. The toxic principles in chocolate are theobromine and caffeine. Baker's chocolate is the most dangerous form since it contains higher concentrations of these drugs, followed by semi-sweet, dark, and then milk chocolate. Signs include vomiting, diarrhea, tremors, difficulty walking, seizures, and heart problems.
Lead poisoning* is uncommon in dogs. Exposure to lead is from eating paint chips from lead-based paint (found in houses painted prior to 1950), and eating lead objects such as shot, fishing sinkers, or counterweights. Signs of poisoning include vomiting, diarrhea, blindness, seizures, and tremors.
Vertigo*, better known as vestibular disease* in dogs, is an uncommon condition in older dogs. Most cases are idiopathic, but it can also be caused by otitis interna, or inner ear infection, tumors, and encephalitis. Signs include nystagmus, head tilt, circling, vomiting, and falling to one side. Idiopathic vestibular disease will usually resolve in a few days to a few weeks.
Anal gland problems are a very common issue with dogs. Disease of the anal glands or anal sacs may include impaction, infection, or abscessation. The dog will periodically discharge a fishy-smelling substance from its anus when they get too full. These glands are normally expressed when the dog defecates.
Shar Pei fever is a condition seen in Shar Peis characterized by recurring fever and swelling of the hocks. Shar Pei fever can result in renal and liver failure through accumulation of amyloid in those organs (amyloidosis).
Dental disease is very common in dogs. Calculus is the most obvious sign of dental disease, but gingivitis progressing to periodontitis is what results in tooth loss. Treatment involves scaling and polishing of the teeth under general anesthesia and treatment of any periodontal disease. Prevention is very important and can be accomplished through the use of special diets or treats, brushing, and plaque prevention gels.
Portosystemic shunt, also known as a liver shunt, is a bypass of the liver by the body's circulatory system. It can be either a congenital or acquired condition.
Perineal hernia is a condition seen in dogs characterized by herniation of abdominal contents through the pelvic diaphragm and causing swelling on one side of the anus.
Primary ciliary dyskinesia* is a disorder causing dysfunction of cilia. In dogs this manifests as sperm immotility and respiratory disease. Signs include nasal discharge, recurring pneumonia, and infertility. Symptoms develop soon after birth.
Cleft lip and palate is occasionally seen in dogs. Difficulty with nursing is the most common problem associated with clefts, but aspiration pneumonia may be seen with a cleft palate.
Vaccine reactions can be considered any type of adverse event stemming from vaccination, including granuloma formation, but most commonly the term vaccine reaction is used to describe a type I hypersensitivity reaction. The most common signs are facial swelling and hives, but more rarely very serious signs such as hypotension and collapse may occur.
Tetanus* is a disease caused by the bacteria Clostridium tetani following wound contamination. Dogs are not very susceptible to tetanus. Signs include difficulty opening the mouth and eating, contraction of the facial muscles, and rigid extension of the limbs. Dogs may also get localized tetanus, signs of which include stiffness of a limb spreading to the rest of the body.
Tracheal collapse is a condition characterized by incomplete formation or weakening of the cartilagenous rings of the trachea. It is most common in small and toy breeds. Signs include a cough (often called a "goose honk cough" due to its sound), especially when excited.
^Mordecai, Adam L.; Bain, Perry J.; Latimer, Kenneth S. "Blastomycosis In Dogs and Cats". College of Veterinary Medicine at the University of Georgia. Archived from the original on 2006-09-14. Retrieved 2006-11-26.Cite uses deprecated parameters (help)
^Edison, Laura; Bain, Perry J.; Latimer, Kenneth S.; Roberts, Royce E. "Canine and Feline Histoplasmosis". College of Veterinary Medicine at the University of Georgia. Retrieved 2006-11-26.Cite uses deprecated parameters (help)
^Reynolds, Cecily A.; Bain, Perry J.; Latimer, Kenneth S. "Canine and Feline Cryptococcosis". College of Veterinary Medicine at the University of Georgia. Archived from the original on 2006-09-11. Retrieved 2006-11-27.Cite uses deprecated parameters (help)
^Cleveland, C. Wyatt; Latimer, Kenneth S.; Peterson, David S. "An Overview of Canine Babesiosis". College of Veterinary Medicine at the University of Georgia. Retrieved 2006-11-28.Cite uses deprecated parameters (help)
^ abPlunkett, Signe J. (2000). Emergency Procedures for the Small Animal Veterinarian. Elsevier Health Sciences. p. 11. ISBN0-7020-2487-2.
^ abFeldman, Bernard F.; Joseph G. Zinkl, Nemi Chand Jain, Oscar William Schalm (2000). Schalm's Veterinary Hematology. Blackwell Publishing. p. 506. ISBN0-683-30692-8.Cite uses deprecated parameters (help)
^Shearman, JR; Wilton, AN. (2007). "Elimination of neutrophil elastase and adaptor protein complex 3 subunit genes as the cause of trapped neutrophil syndrome in Border collies". Animal Genetics38 (2): 188–189. doi:10.1111/j.1365-2052.2007.01565.x. PMID17302793.
^Knight, A.P.; Walter, R.G. (2003). "Plants Affecting the Digestive System". A Guide to Plant Poisoning of Animals in North America. International Veterinary Information Service. Retrieved 2007-01-07.Cite uses deprecated parameters (help)
^Cohen, Michelle, Post, Gerald S. (2002). "Water Transport in the Kidney and Nephrogenic Diabetes Insipidus". Journal of Veterinary Internal Medicine (Journal of Veterinary Internal Medicine) 16 (5): 510–7. doi:10.1111/j.1939-1676.2002.tb02379.x. PMID12322698. (PDF)
^Rijnberk, A, Eigenmann, JE, Belshaw, BE, Hampshire, J, Altszuler, N. (1980). "Acromegaly associated with transient overproduction of growth hormone in a dog". Journal of the American Veterinary Medical Association (Journal-American Veterinary Medical Association) 177 (6): 534–7. PMID7440347.
^Rijnberk A. (2002). "The mammary gland, an endocrine gland". Nederlands tijdschrift voor geneeskunde (Nederlands Tijdschrift voor Geneeskunde (PubMed Summary in English)) 146 (51): 2457–62. PMID12534096.