List of biotechnology companies

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A biotechnology company is a company whose products or services primarily use biotechnology methods for their production, design or delivery. The United Nations Convention on Biological Diversity defines 'biotechnology' as: "Any technological application that uses biological systems, living organisms, or derivatives thereof, to make or modify products or processes for specific use."[1] In other words, biotechology can be defined as the mere application of technical advances in life science to develop commercial products.

Independent biotechnology companies[edit]

2014[edit]

Rank 2013ChangeCompanyCountryMarket Cap in 2013 (USD billions)Market Cap in 2012 (USD billions)% Change over year (Q2-Q2)
1SteadyNovo NordiskDenmark85.33562.80935.9%
2SteadyAmgenUSA78.69555.05442.9%
3SteadyGilead SciencesUSA78.37319.751296.8%
4IncreaseCelgeneUSA52.55734.31953.1%
5DecreaseBiogen IdecUSA47.15731.58249.3%
6DecreaseTeva Pharmaceutical IndustriesIsrael33.76839.292-14.1%
7IncreaseMerck KGaAGermany33.36422.31949.5%
8IncreaseCSLAustralia27.4418.35949.5%
9IncreaseRegeneron20.26911.89470.4%
10SteadyAlexion PharmaceuticalsUSA17.89317.1524.3%
11DecreaseVertex PharmaceuticalsUSA17.4958.151114.6%
12IncreaseUCB (Company)Belgium11.657.44956.4%
13IncreaseBioMarin Pharmaceutical9.0973.3788140.2%
14IncreaseActelionUSA6.8854.54851.4%
15DecreaseDr. Reddy’s LaboratoriesIndia5.0145.0010.3%
16IncreaseSeattle GeneticsUSA4.392.31689.6%
17Gold medal blank.svgAlkermesSwitzerland4.0112.35670.2%
18IncreaseAriad PharmaceuticalsUSA3.32.66814.7%
19Gold medal blank.svgCubist PharmaceuticalsUSA3.0592.66814.7%
20Gold medal blank.svgUnited TherapeuticsUSA2.9662.2631.2%
21Gold medal blank.svgIpsen GroupUSA2.8892.2329.6%
22IncreaseDiaSorinItaly2.62.218%

2013[edit]

Rank 2013ChangeCompanyCountryMarket Cap in 2013 (USD billions)Market Cap in 2012 (USD billions)% Change over year (Q2-Q2)
1SteadyNovo NordiskDenmark85.33562.80935.9%
2SteadyAmgenUSA78.69555.05442.9%
3SteadyGilead SciencesUSA78.37319.751296.8%
4IncreaseCelgeneUSA52.55734.31953.1%
5DecreaseBiogen IdecUSA47.15731.58249.3%
6DecreaseTeva Pharmaceutical IndustriesIsrael33.76839.292-14.1%
7IncreaseMerck KGaAGermany33.36422.31949.5%
8IncreaseCSLAustralia27.4418.35949.5%
9IncreaseRegeneron20.26911.89470.4%
10SteadyAlexion PharmaceuticalsUSA17.89317.1524.3%
11Gold medal blank.svgShire plcUSA17.25217.2050.3%
12DecreaseVertex PharmaceuticalsUSA17.4958.151114.6%
13IncreaseUCB (Company)Belgium11.657.44956.4%
14IncreaseBioMarin Pharmaceutical9.0973.3788140.2%
15SteadyÉlanIreland7.0418.868-20.6%
16IncreaseActelionUSA6.8854.54851.4%
17IncreaseOnyx PharmaceuticalsUSA6.583.01118.6%
18DecreaseDr. Reddy’s LaboratoriesIndia5.0145.0010.3%
19IncreaseSeattle GeneticsUSA4.392.31689.6%
20Gold medal blank.svgAlkermesSwitzerland4.0112.35670.2%
21IncreaseAriad PharmaceuticalsUSA3.32.66814.7%
22Gold medal blank.svgCubist PharmaceuticalsUSA3.0592.66814.7%
23Gold medal blank.svgUnited TherapeuticsUSA2.9662.2631.2%
24Gold medal blank.svgIpsen GroupUSA2.8892.2329.6%
25IncreaseDiaSorinItaly2.62.218%

† Acquired by Amgen in a $10.4 billion deal completed Aug 26 2013 (therefore no longer independent in this list going forward).

NOTE: Market Cap is an indication of the perceived value of the company (&/or its technology) and not necessarily a measure of its size, sales or number of employees; it is indicative of both current and future scale and profitability of the company. The year-on-year change in its value is indicative of the (real or perceived) performance or progress of that company over that year.

Biotechnology companies[edit]

Examining the list of the top 100 such companies, below, shows that many have negative income. This is consistent with the notion that only one in ten biotechnology companies were considered profitable in mid-2005.[4]

Rank 2014CompanyCountryRevenue in 2006 (USD millions)R&D in 2006 (USD millions)Net income/ (loss) in 2006 (USD millions)Employees in 2006
1AmgenUSA14,268.03,366.02,950.020,100
2GenentechUSA11,724.02,995.02,740.010,001+
3GenzymeUSA3,187.0650.0(16.8)9,000+
4UCBBelgium3,169.6772.6461.18,477
5Gilead SciencesUSA3,026.1383.9(1,190.0)7,575
7Biogen IdecUSA2,683.0718.4217.53,750
8CSLAustralia2,148.3119.186.82,895
9CephalonUSA1,764.1403.4144.82,515
10CelgeneUSA898.9258.669.01,864
11ActelionSwitzerland754.6169.0192.41,550
12PDL BioPharmaUSA414.8260.7(130.0)993
13Nektar TherapeuticsUSA217.7149.4(154.8)770
14Vertex PharmaceuticalsUSA216.4371.7(206.9)760
15BioconIndia200.330.543.51,838
16Cubist PharmaceuticalsUSA194.757.4(0.4)746
17Enzon PharmaceuticalsUSA185.743.521.3722
18QLTCanada175.156.4(101.6)653
19AlkermesUSA166.689.13.8617
20CrucellNetherlands165.384.9(110.0)611
21United TherapeuticsUSA159.657.674.0585
22LifeCellUSA141.716.520.5573
23Ligand PharmaceuticalsUSA141.041.9(31.7)540
24Myriad GeneticsUSA114.383.8(38.2)511
25ExelixisUSA98.7185.5(101.5)500
26Emergent BiosolutionsUSAN/AN/AN/AN/A
27InterMuneUSA90.8103.8(107.2)492
28Biota PharmaceuticalsUSAN/AN/AN/AN/A
29BioMarin PharmaceuticalUSA84.266.7(28.5)417
30Lexicon PharmaceuticalsUSA72.8106.7(54.3)410
31Progenics PharmaceuticalsUSA69.961.7(21.6)410
32MorphoSysGermany66.621.97.6336
33Regeneron PharmaceuticalsUSA63.4137.1(102.3)323
34AcambisUK57.068.2(30.4)285
35NPS PharmaceuticalsUSA48.568.4(112.7)276
36Oscient PharmaceuticalsUSA46.212.4(78.5)267
37Array BioPharmaUSA45.033.4(39.6)263
38AEterna ZentarisCanada41.428.733.4260
39IsoTisSwitzerland40.77.7(18.5)255
40Enzo BiochemUSA39.87.9(15.7)255
41CuraGenUSA39.658.5(59.8)254
42Neurocrine BiosciencesUSA39.297.7(107.2)254
43MediGeneGermany38.426.7(8.7)248
44Life TherapeuticsAustralia37.60.1(31.2)245
45Inspire PharmaceuticalsUSA37.142.5(42.1)238
46CV TherapeuticsUSA36.8135.3(274.3)233
47CerusUSA35.629.5(4.8)208
48SciClone PharmaceuticalsUSA32.714.10.7197
49ImmunoGenUSA32.140.9(17.8)197
50ProthericsUK30.911.8(16.5)196
51Arena PharmaceuticalsUSA30.6103.4(88.3)195
52VernalisUK30.171.7(78.2)192
53Bavarian NordicDenmark29.519.9(27.1)191
54XomaUSA29.552.1(51.8)189
55GPC BiotechGermany28.581.3(80.4)180
56TargaceptUSA27.521.8(1.2)170
57Carrington LaboratoriesUSA27.45.8(7.6)166
58Acorda TherapeuticsUSA27.412.1(60.0)158
59Anika TherapeuticsUSA26.83.64.6156
60Dusa PharmaceuticalsUSA25.66.2(31.3)150
61ZymoGeneticsUSA25.4128.5align=right(130.0)150
62MaxygenUSA25.049.1(16.5)147
63Isis PharmaceuticalsUSA24.580.6(45.9)133
64GenmabDenmark23.990.6(77.4)128
65Bioniche Life SciencesCanada24.111.9(1.0)127
66VitrolifeSweden23.23.32.1124
67Medivir GroupSweden18.839.7(29.7)88
68Geron CorporationUSAN/AN/AN/AN/A
69Ambrilia BiopharmaCanada17.48.3(2.1)85
70CytogenUSA17.37.3(15.1)85
71Cayman Chemical CompanyUSA16.23.30.4148
72Sangamo BioSciencesUSAN/AN/AN/AN/A
73Sinovac BiotechChina15.40.3(0.7)67
74Avanir PharmaceuticalsUSA15.229.2(62.6)64
75Synageva BiopharmaUSAN/AN/AN/AN/A

References[edit]

  1. ^ "The Convention on Biological Diversity (Article 2. Use of Terms)." United Nations. 1992. Retrieved on February 6, 2008.
  2. ^ Top 25 Biotech Companies, Genetic Engineering & Biotechnology News, August 2012
  3. ^ Top 100 biotechnology companies, MedAdNews, June 2007
  4. ^ DePalma, Angelo (August 2005), "Twenty-Five Years of Biotech Trends", Genetic Engineering News (Mary Ann Liebert) 25 (14): 1, 14–23, ISSN 1935-472X, retrieved 2008-08-17 

External links[edit]