She made her debut in the Telugu film Egire Paavurama (1996) directed by S. V. Krishna Reddy. Laila began to receive offers from prominent directors to feature in Tamil films and turned down films such as Dharma Chakram and Kadhal Palli by K. S. Ravikumar and Pavithran respectively. She subsequently signed on to appear in the lead role in VIP after Pooja Kumar had walked out of the project. However Laila was left unimpressed when the producer asked her to consider changing her stagename to Pooja, as the invitations for the film had already been printed, and furthermore, she revealed that her unawareness of Rambha also being a part of the film. Laila subsequently dropped out of the project, wanting to make her Tamil debut in a film where she played the sole heroine.
Then came Dhill and Pithamagan with Vikram. In between, Laila took a break and went back to Mumbai. However, she returned to Kollywood with a big bang. Her role in the movie Ullam Ketkumae won her accolades from the masses. She is a very successful Tamil actress.
She got married to Mehdin, an Iranian businessman, on 6 January 2006. She dated him for 7 years before marriage. According to Laila, they were engaged three years before marriage. She now has two sons, and has no intention of returning to movies in the near future. Her mother tongue is Konkani and she belongs to Goan Catholic community however she prefer speaking in English at home.