Lab Rats is an American television sitcom that premiered on February 27, 2012 on Disney XD, which focuses on the life of Leo, whose mother marries billionaire genius Davenport. He meets Adam, Bree, and Chase (Davenport's latest projects), with whom he develops an immediate friendship. The series was created by Chris Peterson and Bryan Moore On January 15, 2011, Billy Unger, who plays Chase, stated that the series was originally called Billion Dollar Freshman. However, the pilot was re-shot, with the changing of the name to Lab Rats, and the addition of Bree, the only girl of the group. In the 19th episode a new character Marcus (Mateus Ward) is entered in to the cast. On May 18, 2012, Lab Rats was renewed for a second season. On July 26, 2013, Disney XD renewed Lab Rats for a third season.
When Leo's mother gets remarried to a billionaire inventor, they move in with him. When trying to find his bedroom, Leo accidentally discovers teenage siblings with bionic powers living in his new basement. Leo takes them to school for the first time and the show follows the bionic teens as they unravel in adventurous situations in an attempt to live life like a normal family in the town of Mission Creek, California.
Chase Davenport (Billy Unger), formerly called "Subject C", is the fifteen-year-old team leader and the youngest with incredible intelligence. He is able to access a vast database of information at any time. Chase can take control over his siblings with his override app in emergencies. He also has a magnetic app. His senses are extremely powerful, including extremely-sensitive hearing and able to see through solid matter. He can also create force-fields, which can be used as a weapon by shrinking them into his hand before launching them. When growing too nervous or angry, he glitches to produce a second personality (dubbed "Spike") that is rude and destructive. A second glitch causes him to produce a sonic sneeze (dubbed "Snot Cannon") when his nose is irritated too much. One of his hidden powers is to manipulate energy around objects to freely move them (dubbed "Molecular Kinesis"). Another hidden ability is to levitate himself. In "Bionic Showdown," it is revealed that Marcus's 'dad' is Chase's 'creator,' not Donald.
Adam Davenport (Spencer Boldman), formerly called "Subject A", is the eighteen-year-old lab rat with super-human strength. He has laser vision that can produce focused yet intense heat beams. When he gets too happy, he can glitch, causing him to create pulse grenades from his hands. His first hidden ability revealed is to generate a powerful force blast of electricity. In "Bionic Showdown", it is revealed that Marcus's dad is Adam's 'creator'.
Bree Davenport (Kelli Berglund), formerly called "Subject B" is the seventeen-year-old lab rat who can move at over 400-miles per hour, create a "sonic-cyclone" by spinning fast, jump exceptionally high, and stick to walls and ceilings. Her speed also grants her equally great dexterity, letting her perform feats like typing with just as much speed. One of her hidden powers is to perfectly replicate any voice or sound she has heard at least once. She is stronger, more agile, and less prone to injury than normal people. When getting too nervous, her sound-mimicking power will cause her to randomly use any/all of them at once. In "Bionic Showdown", it is revealed that Marcus's dad is Bree's bionic creator.
Leo Dooley (Tyrel Jackson Williams) is the fifteen-year-old teen without any abilities. He is considered a social outcast considering his small amount of friends. Donald distrusts Leo due to accidental destruction caused by him. In the second season, Leo is now part of the team. He's also the one who discovers Marcus's true intentions and battles him in "Bionic Showdown" in the Exoskeleton (although he is quickly overpowered and defeated by the stronger Marcus).
Donald Davenport (Hal Sparks) is a thirty-nine-year-old billionaire inventor and Leo's step-father. He is the father-figure and seemingly the creator to all of the Lab Rats, but it is later revealed that Douglas is the true 'father' (creator; they are genetically engineered; their biological parentage remains unclear) of Adam, Bree, and Chase. He usually seems self-centered, childish and a bit selfish, however he does care about Leo and the Lab Rats. He may have been the only one to believe Leo when he said Marcus is evil. After the events in "Bionic Showdown", the lab rats tell Davenport that he is their true father whether or not Douglas was the one who made them.
Note: The names of the Lab Rats—Adam, Bree and Chase—imply that they were originally known as subjects A, B and C. This is further shown by the fact that Adam (Subject A), was born first, followed by Bree (Subject B), and finally Chase (Subject C).
Tasha (Angel Parker) is Leo's mom, Donald's wife, and a TV reporter. She also acts as a mother figure for Adam, Bree, and Chase, but mostly Bree, because she is the only girl in the house.
Eddy (Will Forte) is the five-year-old smart-home system who controls the Lab Rats' house and hates Tasha and the kids but he loves Donald Davenport. He believes Tasha is hideously unattractive.
Principal Perry (Maile Flanagan) is the principal of Mission Creek High School. It is unknown why, but she dislikes Leo the most. Her full name is Terry Cherry Perry, as shown when she and Leo "bond" in "Chip Switch".
Janelle (Madison Pettis) is Leo's crush. Appeared in "Can I Borrow the Helicopter?", "Back From the Future", and "Air Leo". She is very smart but very controlling. Leo mentions in "Can I Borrow the Helicopter?" that she likes comics like him. In "Air Leo", it is revealed that she likes basketball. In "Back From The Future", Future Leo reveals that in the future, he marries Janelle, but when Leo skips his date with her to go save Adam, Bree, and Chase, Future Leo ends up living alone with a dog. Janelle returns in "Avalanche" where she is frozen along with Tasha on Leo's part.
Caitlin (Michaela Carrozzo) is Bree's best friend. In "Robot Fight Club" it was revealed that she wears glasses and also had a crush on Adam. She also develops a crush on Chase at the end of the episode. Appeared in "Death Spiral Smackdown", "Night of the Living Virus", "Robot Fight Club" and "llama drama".
Douglas Davenport (Jeremy Kent Jackson) is the main antagonist of the series. He is Marcus's creator and Donald's younger brother who is planning to capture Adam, Bree, and Chase and to ruin Davenport. In "Bionic Showdown", it is revealed he's Adam, Bree, and Chase's real 'father' (creator; Donald says they are genetically engineered humans, but their biological parentage is still not revealed). Douglas returns in "Avalanche" where he reveals he is just like Chase: He's under-appreciated by his own sibling. Although he tries to manipulate Chase into betraying Leo, Bree, Adam and Donald, Chase double-crosses Douglas and freezes him, saying he would never betray his own family. Donald then has him sent to one of his facilities to be imprisoned.
Marcus Davenport (Mateus Ward) is the fifteen-year-old secondary antagonist of the series. While originally coming off as unceasingly friendly and considerate, it was merely an act to lower suspicion on him and gain other's trust. In "Mission: Space" he installed a hidden spy camera in Davenport's lab. In "Speed Trapped" he revealed to Leo that he is bionic, just like Adam, Bree, and Chase. He threatens to reveal Adam, Bree and Chase's secret if Leo tells anyone the truth about Marcus. In "Leo vs Evil", it is revealed that Marcus has an evil lair right under his house. Also it's revealed that Marcus is working for his father. In "Bionic Showdown", it is revealed that he is an android (but is unaware of it; he thinks he is human) with all of Adam, Bree, and Chase's powers combined and augmented. He was created by Douglas to capture Adam, Bree, and Chase. Douglas says that androids burn out too fast, so he experiment on humans, creating the Lab Rats. Marcus appears to have maybe died at the end of the episode but also might have survived. Marcus is extremely powerful able to easily overwhelm Adam, Bree, and Chase. Marcus was mentioned by Adam twice in Perry 2.0.
Owen (Ben Stillwell) is Bree's new boyfriend and an over-dramatic artist. He first appears in "Quartantined" where Bree snuck out of the house to see his art show. He next appears in "Spike's Got Talent" where he and Adam team up to create a statue of Principal Perry out of butter to stand up to her, but Bree gets jealous and has Eddy melt the sculpture. To make it up to him, she and Adam make a sculpture of Principal Perry out of popcorn.
Ethan (Garrett Backstrom) is Bree's boyfriend. It appears that he and Bree talk math equations to each other. They might have broken up with each other, as shown in "Quarantined". Appeared in "Leo's Jam" and "Smart and Smarter''.
Stephanie (Oana Gregory) is the popular girl at school, who used to be Bree's friend. Appears in "Night of the Living Virus" and "Air Leo". In "Air Leo", it is revealed she's the head cheerleader and lets Adam on the squad, but not Bree because Adam is strong enough to support them when they do the pyramid. When Adam sees Stephanie and her friends being mean to Bree, he quits the squad and cheers with Bree at the One-on-One Basketball Tournament. In "Night of the Living Virus", she and her popular friends come to Bree's sleepover only because of her nice house. When Bree finds out, she kicks her and her friends out.
Trent (Eddie Perino) is the high school jock bully who has an ongoing feud with the Lab Rats. He has competed against them in football and basketball and somehow always seems to come out with the short end of the stick. Appears in "Commando App", "Air Leo" and "The haunting of mission creek high".
Spike (Billy Unger) is Chase's Commando App self who's characterized as jerky, mean, and robust. He glitched and activated in the episode, "Commando App", and made a second appearance in the Season 2 episode, "Spike's Got Talent".
Ms. Thistle (Elizabeth Margaret Beatrice) is an old teacher that covers for Principal Perry in Season 2 episode, "The Haunting of Mission Creek High".