Gramling is a Census-designated place located in Spartanburg County in the U.S. State of South Carolina. According to the 2010 United States Census, the population was 86.
Gramling is located at 35°04′39″N 82°08′05″W / 35.07750°N 82.13472°W (35.077525, -82.134597). These coordinates place the CDP in the Northwestern part of the county, between the Town of Campobello and the City of Inman.
According to the United States Census Bureau, the CDP has a total land area of 1.004 square miles (3.599 km²) and a total water area of 0.009 square miles (0.023 km²).