Fluorometholone

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Fluorometholone
Fluorometholone.png
Systematic (IUPAC) name
(1R,2S,8S,10S,11S,14R,15S,17S)-14-acetyl-1-fluoro-14,17-dihydroxy-2,8,15-trimethyltetracyclo[8.7.0.02,7.011,15]heptadeca-3,6-dien-5-one
Clinical data
AHFS/Drugs.commonograph
MedlinePlusa682660
Pregnancy cat.
  • C
Legal status
?
Identifiers
CAS number426-13-1 YesY
ATC codeC05AA06 D07AB06, D07XB04 (combinations), D10AA01, S01BA07
PubChemCID 9878
DrugBankDB00324
ChemSpider9494 YesY
UNIISV0CSG527L YesY
KEGGD01367 YesY
ChEBICHEBI:31625 N
ChEMBLCHEMBL1200600 N
Synonyms(6S,8S,9R,10S,11S,13S,14S,17R)-17-acetyl-9-fluoro-11,17-dihydroxy-6,10,13-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
Chemical data
FormulaC22H29FO4 
Mol. mass376.462 g/mol
 N (what is this?)  (verify)
 
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Fluorometholone
Fluorometholone.png
Systematic (IUPAC) name
(1R,2S,8S,10S,11S,14R,15S,17S)-14-acetyl-1-fluoro-14,17-dihydroxy-2,8,15-trimethyltetracyclo[8.7.0.02,7.011,15]heptadeca-3,6-dien-5-one
Clinical data
AHFS/Drugs.commonograph
MedlinePlusa682660
Pregnancy cat.
  • C
Legal status
?
Identifiers
CAS number426-13-1 YesY
ATC codeC05AA06 D07AB06, D07XB04 (combinations), D10AA01, S01BA07
PubChemCID 9878
DrugBankDB00324
ChemSpider9494 YesY
UNIISV0CSG527L YesY
KEGGD01367 YesY
ChEBICHEBI:31625 N
ChEMBLCHEMBL1200600 N
Synonyms(6S,8S,9R,10S,11S,13S,14S,17R)-17-acetyl-9-fluoro-11,17-dihydroxy-6,10,13-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
Chemical data
FormulaC22H29FO4 
Mol. mass376.462 g/mol
 N (what is this?)  (verify)

Fluorometholone is a corticosteroid, most often used after laser-based refractive surgery. It is marketed under the brand names FML (Allergan) and Flarex (Alcon).

Fluorometholone acetate ophthalmic suspension is indicated for use in the treatment of steroid responsive inflammatory conditions of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the eye.

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