Fleece is a general term for a soft fabric (often with a deep pile), and may refer to:
- A fleece, a woollen coat of a domestic sheep or long-haired goat, especially after having been sheared (but before being processed into yarn or thread).
- Polar fleece and related modern synthetic materials used to make cool-weather clothing
- Horticultural fleece, used to protect plants from low temperatures or insect pests
- The Golden Fleece of Greek mythology
- To fleece someone, slang term for causing someone to be ripped off, or an unfair transaction