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FDB may refer to:
- Fluid dynamic bearing, type of mechanical bearing
- Fight Dem Back, an Australian and New Zealand anti-racist group.
- Fællesforeningen for Danmarks Brugsforeninger, a consumers' cooperative based in Denmark.
- "FDB" (song), a song by Young Dro
- Frank de Boer, Dutch football manager and former player
- First DataBank, publisher of pharmaceutical information, subsidiary of Hearst Corporation
- Film Development Board, government body developing the motion picture industry in Nepal
- FDB (file format), a computer file format for fonts
- Form Double Byte, Computing file-type
- First Degree Burns, Bristol band