Dyshidrosis

From Wikipedia, the free encyclopedia - View original article

Dyshidrosis
Classification and external resources

Late stage of dyshidrosis on the hands
ICD-10L30.1
ICD-9705.81
DiseasesDB10373
MedlinePlus000832
eMedicinederm/110 ped/1867
MeSHD011146
 
Jump to: navigation, search
Dyshidrosis
Classification and external resources

Late stage of dyshidrosis on the hands
ICD-10L30.1
ICD-9705.81
DiseasesDB10373
MedlinePlus000832
eMedicinederm/110 ped/1867
MeSHD011146

Dyshidrosis (also known as "acute vesiculobullous hand eczema,"[1] "cheiropompholyx,"[2] "dyshidrotic eczema,"[2] "pompholyx,"[2] and "podopompholyx"[2]) is a skin condition that is characterized by small blisters on the hands or feet. It is an acute, chronic, or recurrent dermatosis of the fingers, palms, and soles, characterized by a sudden onset of many deep-seated pruritic, clear vesicles; later, scaling, fissures and lichenification occur. Recurrence is common and for many can be chronic. Incidence/prevalence is said to be 1/5,000 in the United States. However, many cases of eczema are diagnosed as garden-variety atopic eczema without further investigation, so it is possible that this figure is misleading.

This condition is not contagious to others, but its unsightly nature can lend to awkward social interaction. The compromised integument can increase susceptibility to infection, and the accompanying itching can be a source of psychological duress.

The name comes from the word "dyshidrotic," meaning "bad sweating," which was once believed to be the cause, but this association is unproven; there are many cases present that have no history of excessive sweating. There are many different factors that may trigger the outbreak of dyshidrosis such as allergens, stress, or seasonal changes. Emotional stress may also further aggravate the condition.

Contents

Symptoms

Small blisters with the following characteristics:

Causes

Causes of dyshidrosis are unknown. However, a number of triggers to the condition exist:

Diagnosis

Allergy testing is a contested subject among eczema communities. Some dermatologists posit that, if a sufferer is allergic to a substance, then a general allergy test on the forearm will suffice. However, others believe that, with conditions like dyshidrosis, the suspect substances must be applied to the affected area to induce a reaction.

It is often seen in people already susceptible to allergies and/or asthma.

Treatment

There are many treatments available for dyshidrosis. However, few of them have been developed or tested specifically on the condition.

See also

References

  1. ^ James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology (10th ed.). Saunders. ISBN 0-7216-2921-0.
  2. ^ a b c d Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 1-4160-2999-0.
  3. ^ Menne T, Borgan O, Green A. Nickel allergy and handdermatitis in a stratified sample of the Danish female39. Gawkrodger DJ, Vestey JP, Wong W-K, Buxton PK.Contact clinic survey of nickel-sensitive subjects. Contactpopulation: an epidemiological study including a statisticappendix. Acta Derm Venereol 1982; 62: 35–41.
    Gawkrodger DJ, Vestey JP, Wong W-K, Buxton PK.Contact clinic survey of nickel-sensitive subjects. Contactpopulation: an epidemiological study including a statisticappendix. Acta Derm Venereol 1982; 62: 35–41.Dermatitis 1986; 14: 165–169
    Christensen OB, Moller H. Nickel allergy and handitis, and hand and contact dermatitis in adolescents. TheOdense Adolescence Cohort Study on Atopic Diseaseseczema. Contact Dermatitis 1975; 1: 129–135.
    Menne T, Holm NV.
    Hand eczema in nickel-sensitiveand Dermatitis. Br J Dermatol 2001; 144: 523–532.24. Mortz CG, Lauritsen JM, Bindslev-Jensen C, Andersenfemale twins. Genetic predisposition and environmentalfactors. Contact Dermatitis 1983; 9: 289–296.
    Flyholm MA, Nielson GD, Andersen A. Zeitschrift für Lebensmitteluntersuchung und -Forschung. 1984. p. 427-31.
  4. ^ Dermatology 1999;199:308-312 doi:10.1159/000018280
  5. ^ Vol. 140 No. 12, December 2004 Archives of Dermatology Oral Al1itretinoin (9-cis-Retinoic Acid) Therapy for Chronic Hand Dermatitis in Patients Refractory to Standard Therapy Results of a Randomized, Double-blind, Placebo-Controlled, Multicenter Trial Thomas Ruzicka, MD; Frederik Grønhøj Larsen, MD, PhD; Dorota Galewicz, MD; Attila Horváth, MD; Peter Jan Coenraads, MD; Kristian Thestrup-Pedersen, MD; Jean Paul Ortonne, MD; Christos C. Zouboulis, MD; Martin Harsch, PhD; Thomas C. Brown, PhD; Maurice Zultak
  6. ^ "eMedicine - Dyshidrotic Eczema : Article by Camila K Janniger". http://www.emedicine.com/ped/topic1867.htm. Retrieved 2007-07-10.
  7. ^ BIRT AR (March 1964). "Drugs for Eczema of Children". Can Med Assoc J 90 (11): 693–4. PMC 1922428. PMID 14127384. //www.ncbi.nlm.nih.gov/pmc/articles/PMC1922428/.
  8. ^ Stalder JF, Fleury M, Sourisse M et al. (1992). "Comparative effects of two topical antiseptics (chlorhexidine vs KMn04) on bacterial skin flora in atopic dermatitis". Acta Derm Venereol Suppl (Stockh) 176: 132–4. PMID 1476027.
  9. ^ Baron S, Moss C (February 2003). "Caustic burn caused by potassium permanganate". Arch. Dis. Child. 88 (2): 96. doi:10.1136/adc.88.2.96. PMC 1719457. PMID 12538301. http://adc.bmj.com/cgi/pmidlookup?view=long&pmid=12538301.
  10. ^ http://www.dermnet.org.nz/dermatitis/pompholyx.html
  11. ^ MDContact Dermatitis 2007: 57: 203–210 Journal compilation # 2007 Blackwell Munksgaard CONTACT DERMATITIS Management of chronic hand eczema THOMAS L. DIEPGEN, TOVE AGNER, WERNER ABERER, JOHN BERTH-JONES, FRE´ DE´ RIC CAMBAZARD, PETER ELSNER, JOHN MCFADDEN AND PIETER JAN COENRAADS 1Department of Clinical Social Medicine, Occupational & Environmental Dermatology, University Hospital Heidelberg, Heidelberg 69115, Germany, 2Department of Dermatology, University of Copenhagen, Roskilde Sygehus, 4000 Roskilde, Denmark, 3Department of Dermatology, University of Graz, 8036 Graz, Austria, 4Department of Dermatology, University Hospitals Coventry and Warkwickshire NHS Trust, Coventry CV2 2DX, UK, 5Department of Dermatology, 42055 St Etienne, France, 6Department of Dermatology and Allergology, Friedrich Schiller University Jena, 07740 Jena, Germany, 7St Thomas Hospital, St Johns Institute of Dermatology, London, UK, and 8Department of Dermatology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands
  12. ^ Ruzicka T, Lynde C, Jemec G et al. Efficacy and safety of oral alitretinoin in patients with severe chronic hand eczema refractory to topical corticosteroids: results of a randomised, double-blind, placebo-controlled, multicentre trial. British Journal of Dermatology April 2008; 158(4): 808-817.
  13. ^ KAABER, K., VEIEN, N. K. and TJELL, J. C. (1978), Low nickel diet in the treatment of patients with chronic nickel dermatitis. British Journal of Dermatology, 98: 197–201. doi:10.1111/j.1365-2133.1978.tb01622.x

External links