His brother Arie is an offensive tackle at Alabama. On National Signing Day, Kouandjio announced on ESPNU that he would attend Auburn University. Later that day it was reported that he had second thoughts about his choice and was still undecided. Then on February 5, 2011, three days later, Kuandjio's brother Arie announced on his Twitter account that Cyrus would attend the University of Alabama.
2011: Kouandjio contributed as a true freshman, playing in eight games until a knee injury in the second half against Tennessee ended his season.
2012: Kouandjio started all 14 games at left tackle. He had the least number of career starts on the Alabama offensive line in 2012, but only two of the five starters on the offensive line in 2012 (Kouandjio and right guard Anthony Steen) will return for the 2013 season. In the 2013 BCS National Championship Game against Notre Dame, Alabama repeatedly ran to the left behind Kouandjio, contributing to 265 net yards rushing and 5.9 yards per rush. On Alabama's third drive Kouandjio pancake blocked Notre Dame defensive end Sheldon Day. Kouandjio ended the 2012 season ranked as the top offensive tackle from the 2011 recruiting class.