Clayton is an unincorporated community in Stevens County, Washington, United States. Clayton is located along U.S. Route 395 4.5 miles (7.2 km) northwest of Deer Park. Clayton has a post office with ZIP code 99110.
Clayton was founded in 1889 and was named for nearby clay deposits. Clayton was listed as a census-designated place for the 2010 census and has a population of 443.
It was the birthplace of the Hollywood writer Robert Carson, and the residence of artist Leno Prestini.