Brunner's glands

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Brunner's glands
Gray1058.png
Section of duodenum. (Duodenal glands in submucosa are labeled at right, fourth from the top.)
Latinglandulae duodenales
Gray'ssubject #248 1176
 
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Brunner's glands
Gray1058.png
Section of duodenum. (Duodenal glands in submucosa are labeled at right, fourth from the top.)
Latinglandulae duodenales
Gray'ssubject #248 1176

Brunner's glands (or duodenal glands) are compound tubular submucosal glands found in that portion of the duodenum which is above the hepatopancreatic sphincter (Sphincter of Oddi). The main function of these glands is to produce a mucus-rich alkaline secretion (containing bicarbonate) in order to:

They also secrete urogastrone, which inhibits parietal and chief cells of the stomach from secreting acid and their digestive enzymes. This is another form of protection for the duodenum.

They are the distinguishing feature of the duodenum, and are named for the Swiss physician who first described them, Johann Conrad Brunner.

Human brunner's gland

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