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Big River may refer to:
- New Zealand
- United States
- All pages beginning with "Big River"
- Mississippi River (derived from Native American names meaning Big River), the largest river system in North America
- Rio Grande (literal English translation: Big River), a river that forms part of the Mexico – United States border
- Guadalquivir (derived from Arabic الوادي الكبير: Big River), the fifth longest river in Spain and most important in Andalusia