Bacampicillin

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Bacampicillin
Bacampicillin.png
Systematic (IUPAC) name
1-Ethoxycarbonyloxyethyl (2S,5R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
Clinical data
AHFS/Drugs.comMicromedex Detailed Consumer Information
Legal status?
RoutesOral
Pharmacokinetic data
MetabolismRapidly hydrolyzed to ampicillin
Identifiers
CAS number37661-08-8 N
ATC codeJ01CA06
PubChemCID 39849
DrugBankDB01602
ChemSpider390135 YesY
UNII8GM2J22278 YesY
ChEBICHEBI:2968 YesY
ChEMBLCHEMBL1583 YesY
Chemical data
FormulaC21H27N3O7S 
Mol. mass465.519 g/mol
 N (what is this?)  (verify)
 
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Bacampicillin
Bacampicillin.png
Systematic (IUPAC) name
1-Ethoxycarbonyloxyethyl (2S,5R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
Clinical data
AHFS/Drugs.comMicromedex Detailed Consumer Information
Legal status?
RoutesOral
Pharmacokinetic data
MetabolismRapidly hydrolyzed to ampicillin
Identifiers
CAS number37661-08-8 N
ATC codeJ01CA06
PubChemCID 39849
DrugBankDB01602
ChemSpider390135 YesY
UNII8GM2J22278 YesY
ChEBICHEBI:2968 YesY
ChEMBLCHEMBL1583 YesY
Chemical data
FormulaC21H27N3O7S 
Mol. mass465.519 g/mol
 N (what is this?)  (verify)

Bacampicillin (INN) is a penicillin antibiotic. It is a prodrug of ampicillin with improved oral bioavailability.[1]

It is sold under the brand names Spectrobid (Pfizer) and Penglobe (AstraZeneca).

References[edit]

  1. ^ Bodin NO, Ekström B, Forsgren U et al. (November 1975). "Bacampicillin: a New Orally Well-Absorbed Derivative of Ampicillin". Antimicrob Agents Chemother 8 (5): 518–25. PMC 429411. PMID 1211909.