Azapropazone

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Azapropazone
Azapropazone.svg
Azapropazone molecule
Systematic (IUPAC) name
(RS)-5-dimethylamino-9-methyl-2-prop-2-enylpyrazolo[1,2-a][1,2,4]benzotriazine-1,3-dione
Clinical data
Trade namesRheumox
AHFS/Drugs.comInternational Drug Names
Legal status
Pharmacokinetic data
Half-life20 hours
Identifiers
CAS number13539-59-8 N
ATC codeM01AX04
PubChemCID 26098
ChemSpider24310 YesY
UNIIK2VOT966ZI YesY
KEGGD02966 YesY
ChEBICHEBI:38010 YesY
ChEMBLCHEMBL1231131 N
Chemical data
FormulaC16H20N4O2 
Mol. mass300.36 g/mol
 N (what is this?)  (verify)
 
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Azapropazone
Azapropazone.svg
Azapropazone molecule
Systematic (IUPAC) name
(RS)-5-dimethylamino-9-methyl-2-prop-2-enylpyrazolo[1,2-a][1,2,4]benzotriazine-1,3-dione
Clinical data
Trade namesRheumox
AHFS/Drugs.comInternational Drug Names
Legal status
Pharmacokinetic data
Half-life20 hours
Identifiers
CAS number13539-59-8 N
ATC codeM01AX04
PubChemCID 26098
ChemSpider24310 YesY
UNIIK2VOT966ZI YesY
KEGGD02966 YesY
ChEBICHEBI:38010 YesY
ChEMBLCHEMBL1231131 N
Chemical data
FormulaC16H20N4O2 
Mol. mass300.36 g/mol
 N (what is this?)  (verify)

Azapropazone is a non-steroidal anti-inflammatory drug. It is manufactured by Goldshield under the tradename Rheumox.[1]

It was available in the UK as a prescription-only drug, with restrictions due to certain contra-indications and side-effects.[2] Azopropazone has now been discontinued in the British National Formulary.

Azapropazone has a half-life of approximately 20 hours in humans and is not extensively metabolized.[3]

References[edit]

  1. ^ http://home.intekom.com/pharm/cont_eth/rheumox.html
  2. ^ http://www.patient.co.uk/showdoc/30002267/
  3. ^ Jones CJ (1976). "The pharmacology and pharmacokinetics of azapropazone - a review". Curr Med Res Opin 4 (1): 3–16. doi:10.1185/03007997609109361. PMID 770078.