Auto-brewery syndrome

From Wikipedia, the free encyclopedia - View original article

 
Jump to: navigation, search

Auto-brewery syndrome, also known as gut fermentation syndrome, is a rare medical condition in which intoxicating quantities of alcohol are produced through endogenous fermentation within the digestive system.[1][2] Numerous cases have been documented in the medical literature.[3]

Claims of endogenous fermentation of this type have been used as a defense against drunk driving charges.[4][5]

One case[6] went undetected for 20 years.

It has also been investigated, but eliminated, as a possible cause of sudden infant death syndrome.[7]

The antifungal drug fluconazole tends to put an end to the condition.[8]

References[edit]

  1. ^ Michaeleen Doucleff (September 17, 2013). "Auto-Brewery Syndrome: Apparently, You Can Make Beer In Your Gut". NPR. 
  2. ^ Cordell, B.; McCarthy, J. (2013). "A Case Study of Gut Fermentation Syndrome (Auto-Brewery) with Saccharomyces cerevisiae as the Causative Organism". International Journal of Clinical Medicine 04 (7): 309. doi:10.4236/ijcm.2013.47054.  edit
  3. ^ Kaji, H.; Asanuma, Y.; Yahara, O.; Shibue, H.; Hisamura, M.; Saito, N.; Kawakami, Y.; Murao, M. (1984). "Intragastrointestinal Alcohol Fermentation Syndrome: Report of Two Cases and Review of the Literature". Journal of the Forensic Science Society 24 (5): 461–471. doi:10.1016/S0015-7368(84)72325-5. PMID 6520589.  edit
  4. ^ Logan BK, Jones AW (July 2000). "Endogenous ethanol 'auto-brewery syndrome' as a drunk-driving defence challenge". Medicine, science, and the law. Retrieved 2013-02-27. 
  5. ^ Cecil Adams (October 20, 2006). "Designated drunk: Can you get intoxicated without actually drinking alcohol?". The Straight Dope. Retrieved 2013-02-27. 
  6. ^ http://www.gazettelive.co.uk/news/auto-brewery-syndrome-teetotal-teesville-man-6148233
  7. ^ P. Geertinger MD, J. Bodenhoff, K. Helweg-Larsen, A. Lund (1982-09-01). "Endogenous alcohol production by intestinal fermentation in sudden infant death". Zeitschrift für Rechtsmedizin. Springer-Verlag. Retrieved 2013-02-27. 
  8. ^ http://www.scirp.org/journal/PaperInformation.aspx?PaperID=33912 (click the orange "open access" link to top left)