Atelier Ayesha: The Alchemist of Dusk(アーシャのアトリエ ～黄昏の大地の錬金術士～,Asha no Atorie ~Tasogare no Daichi no Renkinjutsushi~?, lit. Atelier Ayesha ~Alchemist of the Ground of Dusk~) is a Japanese role-playing video game developed by Gust. The character designs are by Hidari. It is the fourteenth title in the Atelier series, coming after Atelier Meruru, but has a storyline independent from previous titles in the series. The game is the first installment in the Dusk series. An English language release was published in March 2013 by Tecmo Koei in western regions. A PlayStation Vita version titled Atelier Ayesha Plus: The Alchemist of Dusk (アーシャのアトリエPlus ～黄昏の大地の錬金術士～) was released on March 27, 2014 in Japan. There is also a drama CD and novel based on the game.
Atelier Ayesha stars Ayesha Altugle, a lonely girl who runs a herbalist's workshop. After her grandfather died, Ayesha’s younger sister Nio disappeared when she was gathering herbs. One day, Ayesha sees Nio in a ruin which starts her journey. The goal of the game is to reunite Ayesha with Nio. Overcoming sadness is one of the game’s themes and players will see Ayesha grow as she writes diary entries.
Atelier Ayesha takes place in a new world separate from the Arland saga where the art of alchemy is out of style. Most people forgot about it and Ayesha lives in an ever changing world.
The game proceeds through that the player completes objectives through harvesting items, combat, or fusing items together. Objectives are given as the game's story proceeds. There is however no systematic objectives, and the only goal is to reunite Ayesha with her sister Nio again. Instead, the player will have to find out answers by making their own choices and by so continue the story. 
Combat commences by that the player character comes in contact with an enemy. The battle system is turn-based and the fastest of the participating characters will receive the first turn. The distance between the player's characters and the enemies has an effect on the battle. The game's main character, Ayesha, is the only character in the game who can use items in battle, which is a main element in the game's battle system.  The party of characters can support each other by actions such as defending and attacking, and characters that are close to each other can support each other with attacks. There are also skills and items that are effective within a certain range. When an enemy is attacked from behind, a ”Back Attack” occurs, which will make the attack into a critical hit. 
The player is able to write in a diary by using points obtained from completing objectives. The diary allows the player to look back on the story so far, as well as obtain bonus rewards. 
Ayesha Altugle (アーシャ・アルトゥール,Āsha Arutūru?)Voiced by:Marina Inoue (Japanese), Erika Harlacher (English): The game's main character. Ayesha is a herbalist who ran a small workshop with her grandfather and little sister Nio, until her grandfather passed away and Nio goes missing. Despite being left alone, Ayesha remained upbeat and continued to run the workshop. One day, Ayesha sees an apparition of Nio by her supposed grave. Convinced that her little sister is still alive, Ayesha sets off on a journey to discover the means to save her.
Nio Altugle (ニオ・アルトゥール,Nio Arutūru?)Voiced by:Mariya Ise (Japanese), Kira Buckland (English): Ayesha's younger sister who disappears one day while out gathering herbs. After a long search by Ayesha and nearby villagers found no trace of the girl, Nio is assumed dead, and a gravestone is erected at the place of her disappearance.
Keithgriff Hazeldine (キースグリフ・ヘーゼルダイン,Kīsugurifu Hēzerudain?)Voiced by:Jōji Nakata (Japanese), Richard Epcar (English): An experienced alchemist from another country with a keen interest about ancient times. He’s a calm and collected gentleman in pursuit of knowledge. Keithgriff first encounters Ayesha on one of his visits to an ancient ruin, and points the young girl towards alchemy as the key to saving her younger sister. In battle, Keithgriff doesn’t use a weapon, instead relying on alchemy related attacks, which he summons from his magic ring.
Regina Curtis (レジナ・カティス,Rejina Katisu?)Voiced by:Fumie Mizusawa (Japanese), Wendee Lee (English): An acquaintance of Ayesha who makes a living selling artifacts excavated from ruins. Despite being a girl, she is considered one of the strongest amongst the excavators, a group consisting mainly of heavily built men in their prime. Regina is a sociable and reliable girl with a bunch of younger siblings to take care of.
Wilbell voll Erslied (ウィルベル・ヴォル エルスリート,Uiruberu Boru Erusurīto?)Voiced by:Asami Seto (Japanese), Cristina Valenzuela (English): A girl who comes from a family of witches. Described as being cute and wearing a black pointy hat, Wilbell is a genius when it comes to magic, but knows that she is a long way to be acknowledged by her great-great-grandmother, to whom she looks up. Despite fighting with a broom, Wilbell is still learning to fly as a proper witch.
Linca (リンカ,Rinka?)Voiced by:Ami Koshimizu (Japanese), Julie Ann Taylor (English): A calm and collected swordswoman that acts as Marion Quinn' bodyguard. By Marion's request, she offers her assistance to Ayesha, who in return helps in her efforts to improve her cooking and make other friends, with dubious results.
Juris Grunden (ユーリス・グルンデン,Yūrisu Gurinden?)Voiced by:Kōsuke Toriumi (Japanese), Patrick Seitz (English): A hunter who wants to defeat a dragon and wear its scales as armor. Despite his stoic demeanor, he is very protective of his sister Nanaca, and watches over her from afar as she looks for pasture for their cows. Juris fights using a hatchet and crossbow.
Atelier Ayesha Plus
Atelier Ayesha Plus: The Alchemist of Dusk (アーシャのアトリエPlus ～黄昏の大地の錬金術士～) is a PlayStation Vita port of the game with additional content. It was released in Japan on March 27, 2014This port includes almost all downloadable content that is available for the PlayStation 3 version of the game, such as costumes and characters, as well as new content, such as a harder difficulty to play the game in, new enemies and costumes and the ability to change the members of the party at any time. 
The PS3 version of the game received a Famitsu review score of 34/40, whilst the PS Vita version attained a score of 31/40.
A novel by the name アーシャのアトリエ～ある錬金術士の旅の日記より～ was released on March 26, 2013. The novel details events that was not included in the game, in the form of eight short stories. The novel was written by Toru Shizuki, illustrated by Hiroki Haruse, and published by Koei Tecmo.