As a freshman in 2012, Cooper finished the regular season with 53 receptions for 895 yards and nine touchdowns. In the 2013 BCS National Championship Game, Cooper returned to Miami, where he played high school football, and led all Alabama receivers with 105 yards and 2 touchdowns. On September 20, 2014 Cooper set new career highs in both receptions and a yards in a victory against the University of Florida. Cooper had ten receptions for 201 yards, the first wide receiver to do so since Julio Jones in 2010. He also set a new mark for career touchdown receptions at Alabama with his 19th and 20th touchdowns, surpassing the previous record of 18 held by Dennis Homan.